Results 141 to 150 of about 19,150,051 (295)

The art of play: exploring the roles of technology and social play in museums

, 2011
In this chapter we explore play as a structure to support visitor learning, drawing from international research in museums and interaction design. Play is a key element in cultural development, according to the Dutch historian Johan Huizinga.
Froes, Isabel, Walker, Kevin
core   +1 more source

Fluency and elaboration in dolphin object play: evidence for creativity in behavioral exchanges? [PDF]

Anim Cogn
Adams AH, Themelin M, Manitzas Hill H, Yeater DB, Walker RT, Hirons AC, Dudzinski KM.   +6 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Scalable decision-making for games of imperfect information. [PDF]

Nature
Sokota S, Vinitsky E, Hu H, Fan Z, Kolter JZ, Farina G.   +5 more
europepmc   +1 more source

Fishing in the Amazon: play first, negotiate later [PDF]

From the international Conferences of the Parties (COP Climate and Biodiversity) to local agreements between users sharing resources, reaching consensus in multilat- eral negotiations is a challenge of primary importance to sustainability efforts. It has also become a dynamic field of research within the scientific community, as well as among political
Bonnet, Marie-Paule, Hora, Neriane, Chapuis, Kevin, Le Page, Christophe, Bommel, P., Evangelista Do Vale, Jôine Cariele, Mendes de Melo, Gustavo, Nasuti, Stéphanie   +7 more
openaire   +2 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Playing the field: A retrospective analysis of anterior cruciate ligament injuries and playing position in elite female football (soccer) players. [PDF]

JSAMS Plus
Di Marco J, Fitzgerald K, Fitzpatrick J.
europepmc   +1 more source

Voyages en Europe : 1829-1854 : extraits de sa correspondance / Frédéric Le Play ; publiés par Albert Le Play.

, 2012
Rústic
Le Play, Pierre Guillaume Frédéric.
core  

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

No clear association between time to return-to-play and first additional injury in European professional football players after ACL injury: A media-based study. [PDF]

J Exp Orthop
Marchetti A, Scordo M, Scarpi L, Colotti M, Trobec B, Sabot R, Deodato M, Canton G, Murena L, Piussi R.   +9 more
europepmc   +1 more source