Results 51 to 60 of about 15,550,123 (259)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Effect of stoichiometry on the magnetocrystalline anisotropy of Fe-Pt and Co-Pt from first-principles calculation

, 2014
The effect of stoichiometry on magnetocrystalline anisotropy energy (MAE) of Fe1+xPt1-x and Co1+xPt1-x (-0.5 < x < 0.5) is studied by use of first-principles method. The calculated MAEs show maxima at x = 0 for both fully L1(0)-ordered systems.
Liu, J. P., Ruban, Andrei V.,, Xia, W. X., Ruban, A. V., Yan, A., Du, J., Luo, H. B., Zhang, J.   +7 more
core   +1 more source

First-principles core energies of isolated basal and prism screw dislocations in magnesium

, 2022
We use first-principles energy density method (EDM) to calculate atomic energies for isolated 〈a〉-type basal and prism screw dislocation cores in Mg and compute line energies and core energy differences. The atomic energy distribution in the dislocations
Yang Dan (10920), Dallas R. Trinkle (12274778)   +1 more
core   +1 more source

High‐Temperature Superconductivity of Thermodynamically Stable Fluorite‐Type Hydrides at Ambient Pressure

Advanced Science
Hydride superconductors have attracted significant attention, yet achieving superconductivity at ambient pressure remains a key challenge. Here, a family of high‐Tc (superconducting critical temperature, Tc) hydrides based on the fluorite‐type AXH8 ...
Hongyu Huang, Xiaoyan Yan, Min Wang, Mingyang Du, Hao Song, Zhao Liu, Defang Duan, Tian Cui, Xinmiao Wei   +8 more
doaj   +1 more source

Spin interactions in decorated graphene nanoflakes with two localized spin-1/2 entities

Materials Today Quantum
Magnetic properties of graphene nanoflakes with designed edge shapes are theoretically analyzed by means of the first-principles calculation. As a starting point, we take a nanoflake with decorated zigzag edges where no magnetism is expected. Then, it is
Toshikaze Kariyado
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reinterpretation of the Photoluminescence and Long Persistent Luminescence of Pristine Hexagonal and Cubic CsCdCl3 and with Mn2+ and Fe3+ Doping

Aggregate
The electronic spectra and luminescence decay measurements at room temperature (RT) and 77 K have been recorded for pristine hexagonal and cubic CsCdCl3 and for this material doped with Mn2+ or Fe3+.
Daiwen Xiao, Hei‐Yui Kai, Ka‐Leung Wong, Qiaoling Chen, Anfei Chen, Chang‐Kui Duan, Peter A. Tanner   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source