Results 131 to 140 of about 13,480,937 (242)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

First Aid in Conflict: A view from the occupied Palestinian Territories  

International Journal of First Aid Education
Ibrahim Gholeh
doaj   +2 more sources

First responder airway and compression rate cluster randomized controlled trial: rational and design. [PDF]

Resusc Plus
Rea T, Shin J, Blackwood J, Counts C, Sharar S, Murphy DL, McCoy A, Latimer A, Johnson NJ, Kudenchuk PJ, Sayre M, Brown S, Schmicker R, May S.   +13 more
europepmc   +1 more source

Implementation science in action: national organization of an ambitious first responder training program. [PDF]

Trauma Surg Acute Care Open, 2023
LaGrone L.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Assessment of a County-Wide, Pan-First Responder Take-Home Naloxone Program in Denver, Colorado. [PDF]

J Am Coll Emerg Physicians Open
Jacoves J, Mannerings A, Stader D, Camacho MA, Neuenschwander J, Mason A, Petrasic K, Weiner SG.   +7 more
europepmc   +1 more source

3D Visual Reconstruction as Prior Information for First Responder Localization and Visualization. [PDF]

Sensors (Basel), 2023
Kaiser S, Linkiewicz M, Meißner H, Baumbach D.   +3 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Barriers and facilitators while implementing community first responder systems in a western setting: mixed-methods expert consensus. [PDF]

Int J Emerg Med
Moens E, Degraeuwe E, Caputo ML, Cresta R, Greif R, Baldi E, Barry T, Böttiger BW, Bray J, Busch HJ, Cheskes S, Deakin CD, Doshi AA, Ekkel MM, Elschenbroich D, Fredman D, Gamberini L, Ganter J, Henriksen FL, Jagtenberg CJ, Jonsson M, Khalemsky M, Marks T, Metelmann B, Metelmann C, Monsieurs KG, Müller MP, Ming W, Pooth JS, Prasse S, Salcido DD, Scapigliati A, Schittko N, Schnaubelt S, Scholz SS, Scquizzato T, Shahriari P, Snobelen P, Stieglis R, Strickmann B, Tan HL, Thies KC, Trummer G, Wetsch WA, Vercammen S.   +44 more
europepmc   +1 more source

Out of sight - Out of mind? The need for a professional and standardized peri-mission first responder support model. [PDF]

Resusc Plus, 2023
Schnaubelt S, Orlob S, Veigl C, Sulzgruber P, Krammel M, Lauridsen KG, Greif R.   +6 more
europepmc   +1 more source