Results 61 to 70 of about 13,471,873 (289)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Emergency First Responders’ Misconceptions about Suicide: A Descriptive Study
Nursing ReportsBackground: In 2022, suicide was the second leading cause of external death in Spain (the first among young people aged 15–29 years). This study aims to analyze the presence of myths among emergency first responders and identify the most prevalent false ...
Elena Victoria Ayala Romera +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Confirming the factor structure of the police officer stigma scale
Frontiers in Public HealthFirst responders experience elevated rates of posttraumatic stress disorder (PTSD) depression, and other stress-related conditions due to frequent exposure to critical incidents.
Daniel R. Horning, Clint Bowers
doaj +1 more source
, 2023 In emergency situations, individuals with communication challenges and first responders often experience communication barriers. A Quick Response (QR) code mobile application could bridges these barriers and lead to safe, trauma informed care ...
Lyons, Zara +1 more
core
Live high-train low altitude training: responders and non-responders [PDF]
, 2015 Objective: Investigate differences between athletes that responded (improved performance) compared to those that did not, after a 20-day “live high-train low” (LHTL) altitude training camp.
Manimmanakorn, A +3 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Security Guards and Counter-terrorism: Tourism and Gaps in Terrorism Prevention
International Journal of Religious Tourism and PilgrimageOrganisation operating in the tourism industry are high priority targets for terrorists. In the aftermath of the 9/11 attacks tourism destinations, hotels and modes of public transportation have regularly been targeted by terrorists seeking to convey ...
Luke Howie
doaj +1 more source