Results 101 to 110 of about 1,034,573 (296)

Bifurcations in bosonic stars: chains and rings from spherical solutions

Journal of High Energy Physics
We study the bifurcation phenomena between spherical and axisymmetric bosonic stars. By numerically solving for the zero-modes of spherical bosonic stars under specific axially symmetric perturbations, we discover that excited state spherical bosonic ...
Chen Liang, Carlos A. R. Herdeiro, Eugen Radu   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

First Detection of Shock Waves in RRc Stars

The Astrophysical Journal
Although shock waves have been well documented in fundamental-mode RRab stars, their existence in first-overtone pulsator stars, RRc stars, has remained uncertain. Building upon the spectroscopic frameworks established by M. Chadid et al., we present the
Junzhang Li, Merieme Chadid
doaj   +1 more source

Tracing ωCentauri’s origins: Spatial and chemical signatures of its formation history

Astronomy & Astrophysics
ωCentauri (ωCen), with its unmatched chemical complexity, is the most enigmatic Galactic globular cluster (GC). We combine photometric and spectroscopic catalogs to identify distinct stellar populations within ωCen, investigate their spatial distribution
Dondoglio E., Milone A. P., Marino A. F., Mastrobuono-Battisti A., Bortolan E., Legnardi M. V., Ziliotto T., Muratore F., Cordoni G., Lagioia E. P., Tailo M.   +10 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Kindling the First Stars. I. Dependence of Detectability of the First Stars with JWST on the Population III Stellar Masses

The Astrophysical Journal
The first Population III (Pop III) stars formed out of primordial, metal-free gas, in minihalos at z > 20, and kickstarted the cosmic processes of reionization and enrichment.
Mia Sauda Bovill, Massimo Stiavelli, Alessa Ibrahim Wiggins, Massimo Ricotti, Michele Trenti   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Star Formation at Zero and Very Low Metallicities

, 2007
We describe how star formation is expected to proceed in the early metal-free Universe, focusing on the very first generations of stars. We then discuss how the star formation process may change as the effects of metallicity, external radiative feedback,
McKee, Christopher F., Tan, Jonathan C.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source