Results 231 to 240 of about 14,718,934 (295)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The landscape of artificial intelligence-enabled medical devices in the EU and the US intended for intensive care units. [PDF]

NPJ Digit Med
Freyer O, Buch S, Bassily-Marcus A, Zenker S, Pickering BW, Ostermann M, Schönfelder A, Gilbert S.   +7 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Multi-facility virtual diagnostic for longitudinal phase space predictions. [PDF]

Sci Rep
Lundquist J, Björklund Svensson J, Dijkstal P, Mansten E, Penco G, Werin S, Curbis F.   +6 more
europepmc   +1 more source

AI-based quality control was associated with improved fetal ultrasound image quality in low-resource settings: a real-world multicenter study from West China. [PDF]

BMC Med
Zhao J, Tang Y, Li S, Wang K, Tao J, Chen C, Zhou J, Cui L, Wang Y, Huang C, Liu Z, Kang H, Zhu J, Huang Y.   +13 more
europepmc   +1 more source

Out-of-Hospital Cardiac Arrest: Public-Access Defibrillation and System Approaches to Minimize Avoidable Delay. [PDF]

J Clin Med
Pagnoni G, Bolognesi MG, Bricoli S, Rossi L, Arata A, Aschieri D.   +5 more
europepmc   +1 more source

Usability and Acceptance Testing of an Electronic Patient-Reported Outcome Symptom Monitoring System for People Receiving Immune Checkpoint Inhibitors: Mixed Methods Study. [PDF]

JMIR Form Res
Lai-Kwon J, Rutherford C, Best S, Ferdous HS, Zhang I, Ly TK, Herath D, Burbury K, Jefford M.   +8 more
europepmc   +1 more source

Analysis of Bond Strength of Bioceramic Sealer Following Irrigation with Chlorhexidine. [PDF]

Iran Endod J
Costa LG, Saldanha JM, da Silva-Filho JE, Aguiar BA, de Almeida Gomes F, Gurgel-Filho ED.   +5 more
europepmc   +1 more source

Utility of a Smartphone-Based Clinical Decision Support System for Pressure Ulcer Management by Physicians: Randomized Crossover Pilot Study. [PDF]

JMIR Form Res
Ito T, Hirosawa T, Hayashi A, Yokose M, Shimizu T.   +4 more
europepmc   +1 more source