Results 61 to 70 of about 2,194,446 (266)
The first variation formula for Weyl structures
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Regional and sociodemographic variation of incident first-episode psychosis in Ontario, Canada
Introduction Psychotic disorders are associated with high levels of disability and poor clinical outcomes but little is known about the regional incidence of psychosis in Ontario.
Isobel Sharpe +4 more
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By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
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Cystic duct (CD) variation is challenging for surgeons performing biliary surgery. The misunderstanding of CD variants can lead to iatrogenic bile duct injuries (BDIs).
Zhi-Wei Su, Guo-Xiu Liao
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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The First Variation of an Indefinite Wiener Integral [PDF]
The function u(t) need not be a member of C, but can be any Borel measurable function defined on 0 _ t _ 1, and may even be permitted to take on infinite values. The Wiener integral of a functional is simply the Lebesgue integral of the functional with respect to Wiener's measure [4]1 in C.
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The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
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Endodontic management of a mandibular first molar with four mesial root canals [PDF]
This case report documents the successful endodontic retreatment of a mandibular first molar exhibiting four mesial root canals in a 20-year-old male patient—an exceptionally rare anatomical configuration.
Ali Hasan, Marwa Khalil
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This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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