Results 81 to 90 of about 6,616,017 (286)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Regional and sociodemographic variation of incident first-episode psychosis in Ontario, Canada
Introduction Psychotic disorders are associated with high levels of disability and poor clinical outcomes but little is known about the regional incidence of psychosis in Ontario.
Isobel Sharpe +4 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Cystic duct (CD) variation is challenging for surgeons performing biliary surgery. The misunderstanding of CD variants can lead to iatrogenic bile duct injuries (BDIs).
Zhi-Wei Su, Guo-Xiu Liao
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A well-received generalization in Tagalog is that only the argument that is cross-referenced by voice is eligible for A-bar extraction. However, recent work has shown that agents that are not cross-referenced by voice are also eligible.
Jed Sam Pizarro-Guevara, Matthew Wagers
doaj +2 more sources
The First Variation of an Indefinite Wiener Integral [PDF]
The function u(t) need not be a member of C, but can be any Borel measurable function defined on 0 _ t _ 1, and may even be permitted to take on infinite values. The Wiener integral of a functional is simply the Lebesgue integral of the functional with respect to Wiener's measure [4]1 in C.
openaire +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Endodontic management of a mandibular first molar with four mesial root canals [PDF]
This case report documents the successful endodontic retreatment of a mandibular first molar exhibiting four mesial root canals in a 20-year-old male patient—an exceptionally rare anatomical configuration.
Ali Hasan, Marwa Khalil
doaj +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source

