Results 81 to 90 of about 21,230,810 (314)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Elsie Allan - First World War photograph album

open access: yes, 1914
Album contains photographs taken during the First World War in Victoria and elsewhere in Canada. Places of note in Victoria include Beacon Hill Park, the Gorge Waterway, Government Street and Dallas Road.

core   +1 more source

Destruction  du patrimoine et figure du soldat allemand dans les cartes postales de la Grande Guerre

open access: yesAmnis, 2010
The Great War’s illustrated postcards, specifically concerning topographical views of ruins, in spite of being a neglected source, can still reveal, even after reconstructions have long erased every trace of  war, the impacts of artillery and explosives ...
Emmanuelle Danchin
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

First World War Commemorations in Belgium and the Netherlands: comparative perspectives

open access: yesBMGN: Low Countries Historical Review, 2016
Memory of the First World War is refracted through that of other conflicts. Although these are the first ‘global’ commemorations, national narratives and politics loom large. Commemoration is still dominated by national framing.
Ben Wellings
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Introduction: Children’s Literature and Culture of the First World War

open access: yes, 2016
1914–1964, and is also contributing to several international projects for the centenary of the First World War. Andrea McKenzie is an Associate Professor with York University's Writing Department and Graduate Program in History. She has ..
Johnston, RR, Short, E, Paul, L
core  

Talking about War: dialogues in World War One novels

open access: yesLinguistica, 2018
This article discusses problems involved in the literary representation of argot and spoken language in the context of the First World War based on the analysis of a multilingual corpus including the French novel Le Feu, written by Henri Barbusse in ...
Sabine Bastian, Thomas Sähn
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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