Results 51 to 60 of about 4,078 (260)

FISCAL DISCIPLINE WITHIN THE EU: COMPARATIVE ANALYSIS [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2013
This paper focuses on the analysis of the convergence indicators relative to fiscal area in the EU; subsequent to a description of the main peculiarities of the convergence criteria, the reseach develops a critical analysis on a comparative perspective ...
SORIN CELEA   +2 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The Sustainability Dilemma: Fiscal Rules, Institutional Quality, and Economic Outcomes in the EU

open access: yesSystems
Given that the European Union is facing complex fiscal challenges arising from recent crises, understanding the impact of fiscal rules, institutional governance, and economic performance is critical.
Oana-Ramona Lobonț   +5 more
doaj   +1 more source

Testing the Validity of the Triple Deficit Hypothesis for Nigeria

open access: yesEconometric Research in Finance, 2019
This paper tests the validity of the triple deficit hypothesis in Nigeria by examining the causal relationship among current account deficit, financial account deficit, and fiscal deficit within a five-variate ARDL framework complemented with GMM ...
Rahman Olanrewaju Raji
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Economic, political and institutional determinants of fiscal deficit [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2017
This paper seeks basic economic and political causes of instability and rising fiscal deficit. Economic factors that may cause the appearance and increase in the fiscal deficit are: growth of current public spending, launching public investments, tax ...
Vuković Marija R.
doaj  

Fiscal Discipline and Social Capital: Evidence from Europe during the Last Economic Crisis and Recovery

open access: yesEesti Majanduspoliitilised Väitlused, 2013
The purpose of the current paper is to investigate the possible relationship between fiscal discipline and social capital in EU member states during the last economic crisis and recovery, along with the assessment of the initial welfare effects of fiscal
Eve Parts
doaj   +1 more source

International oversight of fiscal discipline

open access: yesEuropean Journal of Political Research
Abstract Fiscal discipline, the sustainable balancing of government outlays with revenues, is one of the most extensively theorized and empirically investigated objects of inquiry in political economy. Yet, studies covering European Union (EU) countries have mostly ignored the oversight of national budgets via the EU excessive deficit
openaire   +2 more sources

Home - About - Disclaimer - Privacy