Results 61 to 70 of about 4,078 (260)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Regime Specific Fiscal Effects and the Conditional Role of Institutions: The Case of Mexico

Hitit Sosyal Bilimler Dergisi
Institutional quality is a critical element in explaining the inflationary effects of fiscal deficits. Countries with strong institutions can limit the inflationary effects of fiscal deficits by implementing fiscal discipline more effectively.
Seher Gökpınar, Taha Bahadır Saraç
doaj   +1 more source

Specificity of Fiscal Policy in the Monetary Union

Acta Economica, 2018
The condition of the optimal currency area as a theoretical basis of the monetary integration considers the harmonization of the fiscal and monetary policy crucial in achieving the efficient functioning of the monetary union.
Branka Topić-Pavković
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

THE FISCAL FEDERALISM AND THE GOOD ECONOMIC GOVERNANCE IN EUROPEAN UNION [PDF]

Global Economic Observer, 2013
The research objectives aim to analyze the advantages and the disadvantages of the fiscal federalism, in order to identify the model of economic governance that will increase the quality and efficiency in public intervention.
Alina Ligia Dumitrescu
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Finanças públicas e evolução recente da noção de disciplina fiscal Public finance and the recent evolution of the concept of fiscal discipline

Economia e Sociedade, 2012
O objetivo deste artigo é evidenciar a perspectiva de disciplina fiscal atualmente dominante, visando desnaturalizar essa questão tão dogmatizada pelo mainstream.
Neide César Vargas
doaj  

KÜRESEL EKONOMİK KRİZ ÖNCESİ VE KRİZİN ETKİLERİ İLE MÜCADELE SÜRECİNDE AVRUPA BİRLİĞİ’NDE EKONOMİ YÖNETİMİ

Ankara Avrupa Çalışmaları Dergisi, 2012
2008 yılı Eylül ayından itibaren küresel ekonomiyi sarsan kriz, Avrupa Birliği AB ekonomisinin resesyona girmesine sebep olmuş; AB’nin tümünde ekonomik büyüme gerilerken, işsizlik oranları hızla artmıştır.
Dilek Yiğit
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source