Results 61 to 70 of about 1,445,831 (306)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Asian Review of Public AdministrationIn the first quarter of the 21st century, digital transformation emerged as a key catalyst for reshaping public administration systems across Asia. This study examines the transition of public financial management (PFM) systems toward digitalization in ...
Dhanabhadr Sookhdee
doaj +1 more source
Productive Government Expenditure and Fiscal Sustainability [PDF]
FinanzArchiv, 2011 We consider an overlapping-generations model in which public spending directly contributes to an increase in productivity, as in the model of Barro (1990), and in which the government maintains constant ratios of public spending to GDP and of debt issuance to public spending.
openaire +2 more sources
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Committed to Deficit: The Reverse Side of Fiscal Governance [PDF]
Common wisdom dictates that fiscal governance (i.e. procedural fiscal rules) improves fiscal discipline. We rather find that selected fiscal constraints protect the coalitional status quo from logrolling.
Martin Gregor
core
EU governance in the run-up to 2025: A Joint Budgetary Procedure
Perspectives on Federalism, 2016 The Euro Area (Eurozone, or EZ) is navigating uncharted waters; it has started, in slow motion, to slide towards a fiscal federation, while still lacking both the fiscal capacity and the democratic qualification to achieve this goal.
Nicoli Francesco
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Fiscal Policy Coordination in Europe [PDF]
A fundamental overhaul of EU economic governance is needed. The most important reform is a strengthening of national fiscal frameworks, including the establishment of independent fiscal watchdogs in Member States that do not yet have such institutions ...
Calmfors, Lars
core
PRINCIPLES OF THE LEGAL REGIME OF BUDGET FUNDS IN THE CONTEXT OF SOUND PUBLIC FINANCIAL MANAGEMENT
Baltic Journal of Economic StudiesThis article explores the legal and economic principles underlying the legal regime of budget funds, with a view to ensuring sound public financial management. It focuses on identifying and systematising the fundamental principles that govern the use of
Anton Shukhnin +2 more
doaj +1 more source
Digital budget transparency and perceived budget credibility: Technocratic and normative mechanisms in Indonesian local governments [PDF]
Public and Municipal FinanceType of the article: Research Article AbstractBudget credibility is a critical indicator of fiscal reliability in local governments, yet the mechanisms through which digital transparency enhances credibility remain poorly understood. This study examines
Renny Maisyarah
doaj +1 more source