Results 61 to 70 of about 22,171 (312)
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Committed to Deficit: The Reverse Side of Fiscal Governance [PDF]
Common wisdom dictates that fiscal governance (i.e. procedural fiscal rules) improves fiscal discipline. We rather find that selected fiscal constraints protect the coalitional status quo from logrolling.
Martin Gregor
core +1 more source
Governance and Fiscal Federalism in Sudan, 1989–2015: Exploring Political and Intergovernmental Fiscal Relations in an Unstable Polity [PDF]
This report analyses the implementation and impact of decentralisation in Sudan: To what extent has the efforts to implement decentralisation policies actually devolved power and fiscal resources to sub-national levels, for the benefit of the local ...
Gadkarim, Hassan Ali +1 more
core +1 more source
In the first quarter of the 21st century, digital transformation emerged as a key catalyst for reshaping public administration systems across Asia. This study examines the transition of public financial management (PFM) systems toward digitalization in ...
Dhanabhadr Sookhdee
doaj +1 more source
EU governance in the run-up to 2025: A Joint Budgetary Procedure
The Euro Area (Eurozone, or EZ) is navigating uncharted waters; it has started, in slow motion, to slide towards a fiscal federation, while still lacking both the fiscal capacity and the democratic qualification to achieve this goal.
Nicoli Francesco
doaj +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Fiscal Policy Coordination in Europe [PDF]
A fundamental overhaul of EU economic governance is needed. The most important reform is a strengthening of national fiscal frameworks, including the establishment of independent fiscal watchdogs in Member States that do not yet have such institutions ...
Calmfors, Lars
core +1 more source
European Fiscal Policy Coordination and the Persistent Myth of Stabilization [PDF]
[From the introduction]. Institutional and ideological influences are not as important as they might seem at first glance. Seen from Bologna, there are good reasons to doubt the mainstream critique of European macroeconomic governance.
Jones, Erik.
core
Urban governance and finance in India. [PDF]
Over 330 million people live in India's cities; 35 cities have a population of over a million and three (Mumbai, Delhi, and Kolkata) of the 10 largest metropolises in the world are in India.
M. Govinda Rao, Bird, Richard M.
core +3 more sources
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source

