Results 51 to 60 of about 3,724,277 (335)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Fiscal regimes and debt sustainability in Colombia
Journal of Applied EconomicsThis paper evaluates Colombia’s debt sustainability for the period 1980–2021, using a nonlinear fiscal reaction function approach. We employ a Markov-Switching model with annual data to identify sustainable and unsustainable fiscal regimes.
Carlos Andrés Zapata-Quimbayo +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Determinants and consequences of fiscal procyclicality and sustainability [PDF]
, 2012 A countercyclical fiscal policy combined with sustainable fiscal finances is considered to be one of the most important objectives in modern economic policy.
Park, Junho
core
Aligning fiscal and environmental sustainability
SSRN Electronic Journal, 2014 The future of environmental sustainability will be driven by the capacity of local, state and federal levels of government to develop fiscal sustainability. For example, in the case of the Alameda Corridor in Los Angeles County environmental sustainability advanced only because of the fiscal sustaina-bility of the project.
Callahan, Richard, Pisano, Mark
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Assessing fiscal sustainability in Swaziland
South African Journal of Economic and Management Sciences, 2018 Background: Understanding and assessing fiscal sustainability is essential in ensuring financial and macro-economic stability. Fiscal sustainability has emerged as an important subject for Swaziland given the increasingly volatile government revenues ...
Welcome N. Nxumalo, Nomvuyo F. Hlophe
doaj +1 more source
Cogent Economics & Finance, 2023 This paper examines the impact of public debt on fiscal balance. This study uses the standard debt equation in a fiscal reaction and impulse response functions framework to assess the trajectory of public debt and its sustainability within the Sub-Sahara
Gladys A. Abindaw Nabieu +2 more
doaj +1 more source
Compliance with Fiscal Sustainability and the Euro
EmpiricaAbstract Through fiscal reaction functions, we investigate fiscal sustainability for five European country-group panels and check for a change in fiscal behaviour after countries adopted the euro as their currency. Using annual data for the period between 1990 and 2021, we identify evidence of average compliance with sustainability ...
António Afonso +1 more
openaire +3 more sources
Fiscal Sustainability in Aging Societies: Evidence from Euro Area Countries
, 2020 Fiscal sustainability remains a paramount challenge in the Euro Area (EA) countries after the sharp rise in public debt-to-GDP ratios in the aftermath of the financial crisis of 2008.
M. C. Ramos-Herrera +1 more
semanticscholar +1 more source