Results 61 to 70 of about 3,724,277 (335)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

KETANGGUHAN APBN DALAM PEMBAYARAN UTANG

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2011
This paper is designed to analyze the sustainability of the central government budget in the case of Indonesia over the period of 1999-2009. First, we explore the theoretical background of the fiscal sustainability.
Haryo Kuncoro
doaj   +1 more source

Fiscal Sustainability: The Case of Eritrea [PDF]

open access: yesIMF Working Papers, 2004
The paper examines fiscal sustainability issues for the case of Eritrea but has wider implications for addressing fiscal and debt sustainability. It begins with a formal definition and explanation of analytical sustainability indicators, followed by an assessment of the causes of fiscal deficits and their impact on the usual indicators of fiscal and ...
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

ASSESSING FISCAL SUSTAINABILITY OF GOVERNMENT IN IRAN [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2010
This paper investigates the sustainability of fiscal process in Iran. For fiscal process to be sustainable, government's intertemporal budget constraint should be satisfied.
Reza Mosavi Mohseni, Hamed Taheri
doaj  

The "How To" Of Fiscal Sustainability : A Technical Manual For Using The Fiscal Sustainability Tool [PDF]

open access: yes, 2007
Fiscal sustainability analysis (FSA) is an important component of macroeconomic analysis for many developing countries. To further enhance understanding of fiscal policy and the constraints faced by policymakers, the authors develop a toolkit for FSA in middle-income countries which builds on previous work in this area and on new developments in ...
Luca Bandiera   +3 more
openaire   +2 more sources

A wavelet analysis of Italian fiscal sustainability

open access: yesJournal of Economic Structures, 2019
In this paper, we analyse the relationship between public primary deficit and debt for Italian sustainability over the 1862–2013 years. Our empirical strategy uses the wavelet analysis. The empirical evidence suggests the presence of a substantial fiscal
Cosimo Magazzino, M. Mutascu
semanticscholar   +1 more source

The Nexus Between Fiscal Decentralization and Environmental Sustainability in Japan

open access: yesFrontiers in Environmental Science, 2022
This paper adds to the existing body of knowledge by incorporating the role of fiscal decentralization (FD) in influencing CO2 emissions. Therefore, this study looked at the effect of FD on CO2 emissions in the presence of nonrenewable energy consumption
Runsen Yuan   +4 more
semanticscholar   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

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