Results 41 to 50 of about 107,506 (214)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
PARASITE FAUNA OF TAMBAQUI REARED IN NET-CAGES AT TWO STOCKING DENSITIES
This study investigated the parasite fauna in Colossoma macropomum reared at two stocking densities in net-cages of a fish farm in the Matapi River, State of Amapá. Before stocking fish in the net-cages for fattening, fish were examined for parasites and
Raimundo Rosemiro de Jesus BAIA +4 more
doaj +1 more source
The social value of natural aquatic ecosystems is very important to set management priorities. River connectivity is essential for the conservation of freshwater ecosystems because barriers alter both abiotic conditions and the biotic communities ...
Elena Arboleya +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Small streams are important components of the landscape in terra firme forests in central Amazonia and harbor a large number of fish species. Nevertheless, the lack of a common sampling protocol in studies of this ichthyofauna hinders comparisons among ...
Maeda Batista dos Anjos, Jansen Zuanon
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
The five marine protected areas (MPA) covered by this study are located in the barangays of Luban, Lanca and Lawigan in Mati City; Barangay San Ignacio in Manay; and Barangay Jovellar in Tarragona.
Ariel Eballe
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Spatial and temporal variation of fish assemblage structure in a neotropical Mexican river
The introduction of non-native fish into the Teuchitlán River, in west-central Mexico, was suggested as a key factor behind the change in the fish assemblage, and even in the extinction of endemic species. The characterization of the fish assemblage and
Valentin Mar-Silva +6 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source

