Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song +13 more
wiley +1 more source
Correction to "Quantitative Monitoring of Diverse Fish Communities at a Large Scale Combining eDNA Metabarcoding and qPCR". [PDF]
europepmc +1 more source
Elemental Homeostasis Deciphers the Multidimensional Stoichiometric Niche of Fish Communities in the Beibu Gulf. [PDF]
Wang C +8 more
europepmc +1 more source
Soil pH Amelioration Synergizes Carbon Accrual with Yield Gains Under Organic Substitution
Soil pH shifts towards neutrality in both acidic and alkaline soils under organic substitution. A global synthesis links pH amelioration to soil organic carbon accrual through enhanced microbial biomass after accounting for added organic carbon and its interaction with pH. This pH amelioration‐shared soil organic carbon accrual accounts for 5.1–8.6% of
Xunzhuo Dong +7 more
wiley +1 more source
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu +13 more
wiley +1 more source
A fragmented fish community: evaluation of the present distribution and drivers of fish communities in the lower uThukela River, KwaZulu-Natal, South Africa. [PDF]
van Zyl B +3 more
europepmc +1 more source
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu +5 more
wiley +1 more source
Channelization and flow depletion shift benthic macroinvertebrate and fish communities in urban rivers. [PDF]
Chen S +6 more
europepmc +1 more source
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang +10 more
wiley +1 more source
Vulnerability of tropical fish communities across depth in the central Indian Ocean. [PDF]
Stefanoudis PV +12 more
europepmc +1 more source

