Results 91 to 100 of about 790,426 (315)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Influence of geographic origin on post-stocking survival and condition of European grayling (Thymallus thymallus) in a small river

open access: yesAquatic Living Resources, 2018
The post-release survival and condition of 1+ year old European grayling Thymallus thymallus reared in a local (Husinec) and two 250–300 km distant, hatcheries (Pardubice and Hynčice) were evaluated by the recapture of tagged fish five months after ...
Turek Jan   +5 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Evaluating the impact of captive ancestry on the growth and survival of Delta Smelt in a captive environment

open access: yesAquaculture Reports
Delta Smelt Hypomesus transpacificus, is an endangered fish endemic to the California San Francisco Bay-Delta, USA. Extreme declines of the wild Delta Smelt population have prompted use of cultured fish to supplement the wild population since 2021 to ...
Samantha N. Chase   +6 more
doaj   +1 more source

Feeding selectivity and growth of Nile tilapia (Oreochromis niloticus L.) fed on temperate-zone aquatic macrophytes

open access: yesCzech Journal of Animal Science, 2004
Feeding selectivity of Nile tilapia (Oreochromis niloticus L.) juveniles (9.3-20.9 g) to four aquatic macrophyte species and tilapia growth were studied in 4 consecutive experiments. Plant diet was provided to 8 tanks containing 20 fishes for 5 days. The
I. Šetlíková, Z. Adámek
doaj   +1 more source

Development of freshwater prawn (Macrobrachium rosenbergii) seed production and culture technology in the Mekong Delta Region of Vietnam: A review of the JIRCAS Project at Cantho University. [PDF]

open access: yes, 2004
The Mekong Delta of Vietnam is a region rich in aquatic resources having high potential for aquaculture development. Inland aquaculture in the Mekong Delta has greatly increased since the last decade.
Hai, Tran Ngoc   +5 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Culture of fish in rice fields [PDF]

open access: yes
Rice is presently grown in 113 countries. Rice farming also offers a suitable environment for the culture of fish and other aquatic organism. This publication synthesizes the available information on the role that aquaculture can play in rice-based ...
Gupta, M.V. (eds.), Halwart, M.
core  

Fish powder as a low-cost component in media for producing bacterial cellulose [PDF]

open access: yes, 2012
Some bacteria can produce extracellular bacterial cellulose (BC). This polysaccharide is chemically identical to cellulose produced by plants but has no associated lignin and hemicelluloses. The unique mechanical properties, chemical stability and purity
Adnan, Azila Binti   +3 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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