Results 51 to 60 of about 173,982 (316)

Mercury and methylmercury in muscle tissue of chub from the Elbe River main tributaries

open access: yesCzech Journal of Food Sciences, 2008
The aim of the present study was to investigate the concentrations of total mercury and methylmercury in muscle of 55 chub (Leuciscus cephalus) from seven main tributaries (Orlice, Chrudimka, Cidlina, Jizera, Vltava, Ohře, Bílina) of the Elbe River and ...
Kamila KRUŽÍKOVÁ   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A review of the diseases and contaminant related mortalities of tench (Tinca tinca L.)

open access: yesVeterinární Medicína, 2004
The paper provides a review of the current state of knowledge of parasites, diseases and poisonings of tench (Tinca tinca L.) based on the literature and on the authors own findings. Information on the viruses, bacteria, fungi and parasites reported from
Z. Svobodova, J. Kolarova
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Cage fish culture in Nepal

open access: yes, 1979
This paper describes briefly cage fish culture in Nepal with reference to (1) the construction and design of cages; (2) the species used; (3) cage culture practices and results; (4) the economics of cage ...
Sharma, Rama Nath
core  

Alteration in expression of atrogenes and IGF-1 induced by fasting in Nile tilapia Oreochromis niloticus juveniles

open access: yesInternational Aquatic Research, 2017
The growth rate of farmed fish is an important factor regarding aquaculture success. An understanding of the cellular events that occur in skeletal muscle when fish undergo periods of fasting and refeeding provides information useful in developing ...
Caroline Nebo   +4 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Ponds, pond fish, and pond fish culture Kansas Fish and Game Bulletin, No. 01 Part 1.

open access: yes, 1910
"November, 1910."Kansas Forestry Fish and Game Bulletin, No. 1 Part 1Part I. On ponds.--Part II. On pond fish.--Part III.
Kansas State Fish and Game Warden
core  

Effects of microalgae diets on growth, proximate, and fatty acid composition of black mussel, Mytilus galloprovincialis

open access: yesJournal of the World Aquaculture Society
This study evaluates the growth, proximate, and fatty acid composition of black mussel, Mytilus galloprovincialis fed four marine microalgae (Pavlova lutheri, Nannochloropsis oculata, Diacronema vlkianum and Rhinomonas reticulata) diets for 21 days ...
Kamil Mert Eryalçın   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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