Results 41 to 50 of about 206,120 (315)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

First field evidence of aerosolised SGPV, ISAV-HPR0, and IPNV in Atlantic salmon RAS highlights transmission and biosecurity risks

Scientific Reports
Recirculating aquaculture systems (RAS) for Atlantic salmon (Salmo salar L.) are closed-containment systems (CCS) offering biosecure, water-efficient farming conditions, yet pathogen transmission remains a critical concern.
Dhiraj Krishna, Petra Elisabeth Petersen, Maria Marjunardóttir Dahl, Ingibjørg Egholm, Debes Hammershaimb Christiansen   +4 more
doaj   +1 more source

SEROLOGICAL STUDY ON THE PREVALENCE OF MYCOMPLASMA GALLISEPTICUM IN BROILER

The Iraqi Journal of Veterinary Medicine, 1989
Both rapid serum plate agglutination test (RSPT) and Haemagglutination Inhibition test (HIT) were utilized in this study.  Serological data are presented for 244 blood that were collected and examined for the detection of Mycomplasma gallisepticum ...
A. A. H Shalash, A. A. H. Zahid.
doaj   +1 more source

Fish Pathology Research and Diagnosis in Aquaculture of Farmed Fish; a Proteomics Perspective

Animals, 2021
One of the main constraints in aquaculture production is farmed fish vulnerability to diseases due to husbandry practices or external factors like pollution, climate changes, or even the alterations in the dynamic of product transactions in this industry.
Márcio Moreira, Denise Schrama, Ana Paula Farinha, Marco Cerqueira, Cláudia Raposo de Magalhães, Raquel Carrilho, Pedro Rodrigues   +6 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Streptococcus dysgalactiae: An emerging pathogen of fishes and mammals

International Journal of Veterinary Science and Medicine, 2013
Streptococcus dysgalactiae subsp. dysgalactiae (GCSD) has gained special interest of aquatic health experts throughout the past few years due to its interesting veterinary and public health importance.
Mohamed Abdelsalam, Abdellatif Asheg, Alaa Eldin Eissa   +2 more
doaj   +1 more source

Polymerase chain reaction for detection of some highly dangerous viral fish disease agents

Ветеринария сегодня, 2020
Today viral fish diseases cause major losses in the world aquaculture. Pathogen spread often occurs during the transportation of fish from infected farms to the disease-free ones.
A. S. Tarasova, A. V. Perchun, V. P. Melnikov   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Fish skin microbiota under healthy and diseased conditions [PDF]

, 2022
Ashraf Al‐Ashhab, Rivka Alexander‐Shani, Yosef Avrahami, Roberto Erlich, Rosa Ines Strem, Shiri Meshner, Noam Shanital, Galit Sharon   +7 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source