Results 61 to 70 of about 209,501 (267)
Scientific ReportsRecirculating aquaculture systems (RAS) for Atlantic salmon (Salmo salar L.) are closed-containment systems (CCS) offering biosecure, water-efficient farming conditions, yet pathogen transmission remains a critical concern.
Dhiraj Krishna +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Dietary nanocomposite of vitamin C and vitamin E enhanced the performance of Nile tilapia
Scientific ReportsNowadays, nanomaterials enter high numbers of daily used products and drug manufacture. A nanocomposite of vitamins C (VC) and vitamin E (VE) with chitosan as a vehicle and protector was used in a comparative eight-week feeding study, Nile tilapia ...
Ahmed H. Sherif +4 more
doaj +1 more source
Myxozoan fish diseases: possible treatment and zoonoses. [PDF]
J Parasit Dis, 2023 Banu H, Rathinam RB.
europepmc +1 more source
Viral diseases of fish in Japan
Annual Review of Fish Diseases, 1991 Viruses causing infectious pancreatic necrosis (IPN) and infectious hematopoietic necrosis (IHN) were first isolated in Japan during the 1970s and these two diseases remain among the most serious problems affecting cultured salmonids in Japan. In addition to IHN and IPN, four other viral diseases cause major economic losses among cultured fishes in ...
Kimura, Takahisa, Yoshimizu, Mamoru
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The first Report of The Parasitic Copepod Bomolochus unicirrus (Copepoda: Bomolochidae) From Turkey
Turkish Journal of Agriculture: Food Science and Technology, 2017 In this study, Bomolochus unicirrus Brian, 1902, a species of parasitic copepod belonging to the family Bomolochidae (Claus, 1875), was reported for the first time from the north-eastern Mediterranean waters off the Turkish coast.
İbrahim Demirkale +2 more
doaj +1 more source
Advanced Techniques for the Intelligent Diagnosis of Fish Diseases: A Review. [PDF]
Animals (Basel), 2022 Li D, Li X, Wang Q, Hao Y.
europepmc +1 more source