Results 41 to 50 of about 209,501 (267)

MONITORING OF SEASONAL PARASITIC AND MYCOTIC PROBLEMS AFFECTING CULTURED OREOCHROMIS NILOTICUS UNDER SEMI-INTENSIVE SYSTEM [PDF]

open access: yesAssiut Veterinary Medical Journal, 2010
  The study was carried out on 1000 Tilapia (O. niloticus) collected from private and governmental semi intensive earth pond (Central Laboratory for Aquatic Research laboratory (Abbassa) in Sharkia Province, through the seasons of the year 2008.
SOFIA ABOTORKIA   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Severe Outbreak of Saprolegnia Spp. Infection in Spotted Snakehead (Channa punctata, Bloch 1793): Clinical Assessment, Histopathology, Haemato‐Biochemical Indices and Insights Into Therapeutic Effects

open access: yesVeterinary Medicine and Science
Saprolegniasis, caused by Saprolegnia spp., is one of the most lethal oomycete infections affecting freshwater fish. This study investigated a severe fungal infection in Channa punctata (n = 150) fish obtained from a pen culture in the Tanguar haor ...
Md. Shaif Rahman   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

THE CURRENT METHODS FOR MOLECULAR DIAGNOSTICS OF FISH DISEASES (REVIEW)

open access: yesRibogospodarsʹka Nauka Ukraïni, 2016
Purpose. The methods of molecular diagnostic (MMD) gradually become widespread in modern fish farming. MMD contain a wide variety of specific approaches, each of which has distinct limits of their possible applications and is characterized by individual ...
O. Zaloilo   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Fish oils and cardiovascular disease [PDF]

open access: yesBMJ, 1995
EDITOR,—In their editorial B N C Pritchard and colleagues concluded that fish oils have beneficial effects on lipids and the haemostatic system, but they pressed for more studies in diseases related to atherosclerosis.1 We wish to reinforce this …
A, Haines, J S, Yudkin
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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