Results 81 to 90 of about 209,501 (267)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Egyptian Journal of Aquatic Research, 2018 This study was carried out to identify isopod species implicated in the outbreak that had affected commercially important fishes of Lake Qaroun. The study also aims to determine its deleterious effects on infested fish and its possible role in the severe
Nadia G. Ali, Ibrahim M. Aboyadak
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
SEROLOGICAL STUDY ON THE PREVALENCE OF MYCOMPLASMA GALLISEPTICUM IN BROILER
The Iraqi Journal of Veterinary Medicine, 1989 Both rapid serum plate agglutination test (RSPT) and Haemagglutination Inhibition test (HIT) were utilized in this study. Serological data are presented for 244 blood that were collected and examined for the detection of Mycomplasma gallisepticum ...
A. A. H Shalash, A. A. H. Zahid.
doaj +1 more source
Molecular epidemiology of helminth diseases of the humpback grouper, Cromileptes altivelis, as a pattern for mapping fish diseases in the Sunda Strait, Indonesia. [PDF]
Vet World, 2021 Subekti S +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Streptococcus dysgalactiae: An emerging pathogen of fishes and mammals
International Journal of Veterinary Science and Medicine, 2013 Streptococcus dysgalactiae subsp. dysgalactiae (GCSD) has gained special interest of aquatic health experts throughout the past few years due to its interesting veterinary and public health importance.
Mohamed Abdelsalam +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source