Results 101 to 110 of about 11,848,553 (391)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A PRELIMINARY STUDY OF THE PREVALENCE OF ANTIBODIES TO INFECTIOUS BURSAL DISEASE IN BROILER CHICKENS

open access: yesThe Iraqi Journal of Veterinary Medicine, 1987
Infectious bursal disease is one of the diseases frequently diagnosed in broilers chickens in _ Iraq depending on pathological changes in the bursa of Fabricius. It is known that maternal antibodies may interfere with the clinical signs, severity of the
M. A. Al-Attar , K. K. Salman
doaj   +1 more source

Fisheries in a changing scene [includes section on proposed Morecambe Bay barrage scheme]: paper presented at Association of River Authorities, Annual Conference, Morecambe, 1967 [PDF]

open access: yes, 1967
The report looks at trends developing in the area of the Lancashire River Authority which will, by the turn of the century, bring tremendous pressures to bear on its natural resources, particularly land and water.
Stewart, L.
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

First Report of Haplosporidium edule Infection in the Olive-Green Cockle (Cerastoderma glaucum) from the Northern Adriatic Sea: Expanding Host Range and Geographic Distribution

open access: yesPathogens
Haplosporidium edule is a haplosporidian parasite originally described in the common edible cockle (Cerastoderma edule) along the European Atlantic coast. In this study, we report the first detection of H.
Alessia Vetri   +10 more
doaj   +1 more source

Histopathological alterations and condition factor deterioration accompanied by isopod infestation in Tilapia zilli, Mugil capito and Solea aegyptiaca from Lake Qaroun

open access: yesEgyptian Journal of Aquatic Research, 2018
This study was carried out to identify isopod species implicated in the outbreak that had affected commercially important fishes of Lake Qaroun. The study also aims to determine its deleterious effects on infested fish and its possible role in the severe
Nadia G. Ali, Ibrahim M. Aboyadak
doaj   +1 more source

IN-VITRO INHIBITION TEST OF KEJI BELING (STROBILANTHES CRISPUS) CRUDE EXTRACT ON EDWARDSIELLA TARDA [PDF]

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2022
Bacterial infections, such as Edwardsiella tarda, can cause fish diseases. The onset of the disease is the least expected by the cultivators because it can result in economic losses.
Heny S., Arief P., Manggar R.N.V.
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

SEROLOGICAL STUDY ON THE PREVALENCE OF MYCOMPLASMA GALLISEPTICUM IN BROILER

open access: yesThe Iraqi Journal of Veterinary Medicine, 1989
Both rapid serum plate agglutination test (RSPT) and Haemagglutination Inhibition test (HIT) were utilized in this study.  Serological data are presented for 244 blood that were collected and examined for the detection of Mycomplasma gallisepticum ...
A. A. H Shalash, A. A. H. Zahid.
doaj   +1 more source

Senegalese sole (Solea senegalensis) ISG15: molecular characterization and in vivo interplay with viral infections [PDF]

open access: yes, 2015
The interferon-stimulated gene 15 (Isg15) is strongly induced by type I interferon (IFN I), viral infection, and double-stranded RNA (poly I:C) in several fish species, suggesting that Isg15 protein could play a key role in fish innate immunity against ...
Alonso-Sanchez, Maria del Carmen   +5 more
core  

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