Results 71 to 80 of about 226,406 (314)

Occurrence of virulence factors and antimicrobial susceptibility of Citrobacter freundii isolated from diseased ornamental fish in Poland

Journal of Veterinary Research
Citrobacter freundii strains, like other representatives of the same genus, are often described as aetiological factors of diseases in humans and animals, including farmed and ornamental fish.
Pastuszka Anna, Guz Leszek, Puk Krzysztof, Pietras-Ożga Dorota   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Mortality outbreak in turbot (Psetta maxima) farmed in Italy. [PDF]

, 2023
Introduction: Turbot (Psetta maxima) is one of the most important fish species in European aquaculture. The increase of its production should pass through the overcoming of some zootechnical and health issues, among which several transmissible diseases ...
Gustinelli, Andrea, Quaglio, Francesco, Bignami, Giorgia, Maria Letizia Fioravanti., Caffara, Monica   +4 more
core  

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

First field evidence of aerosolised SGPV, ISAV-HPR0, and IPNV in Atlantic salmon RAS highlights transmission and biosecurity risks

Scientific Reports
Recirculating aquaculture systems (RAS) for Atlantic salmon (Salmo salar L.) are closed-containment systems (CCS) offering biosecure, water-efficient farming conditions, yet pathogen transmission remains a critical concern.
Dhiraj Krishna, Petra Elisabeth Petersen, Maria Marjunardóttir Dahl, Ingibjørg Egholm, Debes Hammershaimb Christiansen   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Survey on zoonotic parasites in wild freshwater fish from Italy. [PDF]

, 2011
Results of a survey on zoonotic parasites in wild freshwater fish from Italy carried out in 2009-2011 are reported and ...
CAFFARA, MONICA, GUSTINELLI, ANDREA, Prearo M., FIORAVANTI, MARIALETIZIA   +3 more
core  

Dietary nanocomposite of vitamin C and vitamin E enhanced the performance of Nile tilapia

Scientific Reports
Nowadays, nanomaterials enter high numbers of daily used products and drug manufacture. A nanocomposite of vitamins C (VC) and vitamin E (VE) with chitosan as a vehicle and protector was used in a comparative eight-week feeding study, Nile tilapia ...
Ahmed H. Sherif, Riad H. Khalil, Talaat S. Talaat, Mohamed Z. Baromh, Mahmoud A. Elnagar   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source