Results 81 to 90 of about 1,826,528 (232)

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

Advanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias, Carmen Domínguez‐Alonso, Ivana Zagorac, Antonio Tapia‐Galisteo, Eva García‐Veros, Laura Rubio‐Pérez, Marina Gómez‐Rosel, Patricia Fuentes, Patricia Hernández‐López, Óscar Aguilar‐Sopeña, Laura Almagro‐Puente, Sonia Martínez‐González, Lucía Cañizares‐Moscato, María Rivas‐Sánchez, Belén Blanco, Ángel Ramírez‐Fernández, Laura Díez‐Alonso, Carmen Blanco‐Aparicio, Javier Arroyo‐Ródenas, Jorge Martínez‐Torrecuadrada, María L. Toribio, Pedro Roda‐Navarro, Anaïs Jiménez‐Reinoso, Luis Álvarez‐Vallina   +23 more
wiley   +1 more source

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

Advanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo, Seon Min Woo, Minhyeong Choi, Soeun Rhee, Simmyung Yook, Donghyuk Shin, Kwang‐Su Park, Taeg Kyu Kwon   +7 more
wiley   +1 more source

Fish Commission research briefs. Vol. 1, no. 1

These short reports are intended to inform the public, industry, and other interested parties of the current studies of the Commission's staff and the basis for conservation measures.
Oregon. Fish Commission
core   +3 more sources

PRODUCTIVITY OF SELAMBAU (FILTERING DEVICE) OPERATED IN THE WATERS OF SAPALA VILLAGE, SOUTH KALIMANTAN PROVINCE, INDONESIA [PDF]

Russian Journal of Agricultural and Socio-Economic Sciences
The objectives of this research are: 1) Describe the Selambau used in the waters of Sapala Village, Paminggir District, Hulu Sungai Utara Regency, South Kalimantan Province; 2) Analyze the composition and proportion and frequency of appearance of fish ...
Iriansyah, Riyandi A.
doaj  

OsCPK12‐OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice

Advanced Science, EarlyView.
OsCPK12 interacts and phosphorylates OsAtpD1 at Ser8 in its transit peptide. This phosphorylation promote its chloroplast translocation, thereby maintaining ATP synthase activity and proton gradient (ΔpH) homeostasis and regulating photosynthetic acclimation, photoprotection, and repair under light stress.
Beifang Wang, Aaron Chan, Yongyi Fan, Yanwu Wang, Pao Xue, Yingxin Zhang, Xiaodeng Zhan, Weixun Wu, Ping Yu, Daibo Chen, Junlin Fu, Yongbo Hong, Xihong Shen, Lianping Sun, Aike Zhu, Shihua Cheng, Qunen Liu, Liyong Cao   +17 more
wiley   +1 more source

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

Advanced Science, EarlyView.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo, Yonghyeon Kim, Nangyeong Hwang, Gwanho Sung, Sujin Jo, Yeonhu Lee, Ho‐Chul Kang, Jae‐Ho Lee, Yong Won Choi, Hyeseong Cho, Sunwoo Min   +10 more
wiley   +1 more source

Analysis of productive and biological parameters of age-1+ carp crossbreed obtained by synthetic selection method in the Polissya zone of Ukraine

Ribogospodarsʹka Nauka Ukraïni
Purpose. To provide a comprehensive productive and biological characteristic and conduct a comparative analysis of the main productive parameters between purebred age-1+ Lyubin scaly carps and crossbreeds, which were obtained from crossing the offspring ...
H. Kurinenko, U. Kuts, М. Ostapchuk, S. Yurchak   +3 more
doaj   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Size spectra assess social-ecological impacts on Amazonian fish assemblages

Ecological Indicators
Finding easily accessible indicators to assess the biodiversity conservation is crucial in regions where long-term monitoring data is deficient. This is particularly true for tropical freshwater ecosystems, which house most of the known fish biodiversity
Victoria J. Isaac, Leandro Castello, Nelson A. Gouveia, Jansen A.S. Zuanon, Fernanda A. Martins, Rivetla Edipo Araujo Cruz, Rodrigo O. Campos, Caroline C. Arantes, Gabriel C. Borba, Morgana Carvalho de Almeida, Claudia Pereira de Deus, Carolina R.C. Dória, Marilia Hauser, Carlos E. Freitas, Tommaso Giarrizzo, Alexandre P. Hercos, Giulia C. Lopes Carvalho, Elineide E. Marques, Raimundo Nonato G. Mendes-Júnior, Ualerson Iran Peixoto, Nelson Silva Pinto, Renato A.M. Silvano, Flavia K. Siqueira Souza, Ariana Cella-Ribeiro, Gislene Torrente-Vilara, Kedma C. Yamamoto, Filipe M. França   +26 more
doaj   +1 more source

CLIMATE CHANGES AND CURRENT STATE OF BIOTA IN THE RUSSIAN WATERS OF THE FAR-EASTERN SEAS

Известия ТИНРО, 2019
Discussion about limiting influence of climate conditions on dynamics of the pacific salmon populations and generally on biological resources of the Far-Eastern Seas is continuing.
V. P. Shuntov, O. A. Ivanov
doaj   +1 more source