Results 101 to 110 of about 1,997,597 (283)

Analysis of productive and biological parameters of age-1+ carp crossbreed obtained by synthetic selection method in the Polissya zone of Ukraine

Ribogospodarsʹka Nauka Ukraïni
Purpose. To provide a comprehensive productive and biological characteristic and conduct a comparative analysis of the main productive parameters between purebred age-1+ Lyubin scaly carps and crossbreeds, which were obtained from crossing the offspring ...
H. Kurinenko, U. Kuts, М. Ostapchuk, S. Yurchak   +3 more
doaj   +1 more source

CLIMATE CHANGES AND CURRENT STATE OF BIOTA IN THE RUSSIAN WATERS OF THE FAR-EASTERN SEAS

Известия ТИНРО, 2019
Discussion about limiting influence of climate conditions on dynamics of the pacific salmon populations and generally on biological resources of the Far-Eastern Seas is continuing.
V. P. Shuntov, O. A. Ivanov
doaj   +1 more source

A Tumor‐Boundary Niche Enriched for PD‐1+CD8+T Cells and BTLA+B Cells Drives Resistance to Immunotherapy in NSCLC

Advanced Science, EarlyView.
A spatial niche composed of BTLA+B cells and CD8+T cells is enriched at the tumor boundary in non‐small cell lung cancer. Within this specialized niche, BTLA+B cells act as a dominant source of IL‐6, upregulating PD‐1 on CD8+T cells via STAT3 signaling.
Jiajuan Wu, Shiying Guo, Leilei Lv, Guiqin Fan, Yu Shen, Qiuxia Qu, Cheng Chen   +6 more
wiley   +1 more source

Size spectra assess social-ecological impacts on Amazonian fish assemblages

Ecological Indicators
Finding easily accessible indicators to assess the biodiversity conservation is crucial in regions where long-term monitoring data is deficient. This is particularly true for tropical freshwater ecosystems, which house most of the known fish biodiversity
Victoria J. Isaac, Leandro Castello, Nelson A. Gouveia, Jansen A.S. Zuanon, Fernanda A. Martins, Rivetla Edipo Araujo Cruz, Rodrigo O. Campos, Caroline C. Arantes, Gabriel C. Borba, Morgana Carvalho de Almeida, Claudia Pereira de Deus, Carolina R.C. Dória, Marilia Hauser, Carlos E. Freitas, Tommaso Giarrizzo, Alexandre P. Hercos, Giulia C. Lopes Carvalho, Elineide E. Marques, Raimundo Nonato G. Mendes-Júnior, Ualerson Iran Peixoto, Nelson Silva Pinto, Renato A.M. Silvano, Flavia K. Siqueira Souza, Ariana Cella-Ribeiro, Gislene Torrente-Vilara, Kedma C. Yamamoto, Filipe M. França   +26 more
doaj   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

Advanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang, Yu‐Xuan Bai, Geng G. Tian, Bin Zhang, Ding‐Yi Lu, Qing‐Ping Yao, Wen‐Hao Tian, Xiao‐Na Wei, Jing‐Ting Yang, Ze‐Yu Xiong, Yi Lu, Yu‐Tong Jiang, Chun‐Hui Cai, Yu‐Ming Lu, Xian‐Qing Jia, Li‐Li Jing, Bao‐Jun Yang, Ying‐Xin Qi, Xin‐Xin Han, Ji Wu, Wen‐Hui Lin   +20 more
wiley   +1 more source

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

Advanced Science, EarlyView.
CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai, Jingyi Tang, Huan Rong, Yu Wang, Xiangyi Zhou, Can Xu, Jianhua Wang, Lili Li, Yue Wu, Fei Deng, Dan Yang, Xiao Yang, Renyan Li, Yongzhong Wu, Dongxi Xiang, Tingxiu Xiang   +15 more
wiley   +1 more source

Letter from Mother Fish, Partridge Island, [New York?], to her son, Edmund Fish, Bellevue Hospital, New York, August 21, 1863

A letter sent from Mother Fish to her son Edmund Fish, in Bellevue Hospital.
Fish, Mother
core  

MONITORING ZOOBENTOS PRODUCTIVITY AT THE REGULATED SURA RIVER SECTION IN PENZA REGION

Известия высших учебных заведений. Поволжский регион: Естественные науки, 2020
Background. Zoobenthos is an essential component of the fish food base. Therefore, an assessment of fish productivity for this indicator is necessary for any comprehensive fisheries research in water bodies.
A. Yu. Asanov
doaj   +1 more source

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

Advanced Science, EarlyView.
TROP2 is identified as a novel tumor‐selective lysosomal‐targeting receptor with established clinical relevance. TROP2‐targeting chimeras (TRTACs) are developed by genetically fusing a TROP2‐binding nanobody to nanobodies against specific target proteins.
Luping Chen, Xinying Fu, Wenqian Dong, Xiaobei Deng, Simin Chen, Fujun Wang, Jian Zhao, Shiqun Shao, Liqiang Fan, Jingyu Zhang, Lixin Zhang   +10 more
wiley   +1 more source