Results 221 to 230 of about 309,843 (311)

Effect of cell retention techniques in Komagataella phaffii lab‐scale continuous processes

Biotechnology Progress, EarlyView.
Abstract Perfusion technologies play a growing role in the implementation of continuous processes for biotherapeutics production in mammalian‐based manufacturing. However, their application to alternative production hosts is limited. Cell retention systems are of key importance for the efficiency of perfusion bioreactors.
Marina Y. Linova, Satish K. Kodiripaka, Edite Martins, Sobhana A. Sripada, Stefano Menegatti, John M. Woodley   +5 more
wiley   +1 more source

Relative abundance and diversity of sharks and predatory fishes across Marine Protected Areas of the Tropical Eastern Pacific. [PDF]

PLoS One
McKinley SJ, Hansen SF, Fierro-Arcos D, Cundy ME, Mossbrucker M, Vianna GMS, Suarez-Moncada J, Hoyos-Padilla M, Bessudo-Lion S, Sala E, Salinas-de-León P.   +10 more
europepmc   +1 more source

Shifting baselines, marine reserves, and Leopold’s Biotic Ethic. [PDF]

, 2003
Bohnsack, James A.
core  

Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach

Biotechnology Progress, EarlyView.
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya, Rajesh K. Mistry, Susie Sou, Sonja Hess, Bijay Khanal, Zayla Schaeffer, Jie Zhu, Lina Chakrabarti   +7 more
wiley   +1 more source

Urea use drives niche separation between dominant marine ammonia oxidizing archaea. [PDF]

Nat Commun
Stuehrenberg J, Kitzinger K, von Arx JN, Graf JS, Lavik G, Littmann S, Milucka J, Orsi WD, Schorn S, Speth DR, Vuillemin A, Wu S, Marchant HK, Kuypers MMM.   +13 more
europepmc   +1 more source

Evaluation of gene editing in CHO cells using the Cas‐CLOVER system

Biotechnology Progress, EarlyView.
Abstract Recent advances in gene editing technologies have transformed the genetic engineering of Chinese hamster ovary (CHO) hosts, enabling the development of cell lines with improved stability and productivity. In this study, we employed the programmable nuclease (PN) Cas‐CLOVER to precisely target the Glutamine synthetase (GS) locus in CHO cells. A
Tiffany McLamarrah, Efecan Aral, Michael Hoffman, Jennifer Tedstone, Thomas King, Jason Vitko, Maria João Sebastião, Jose M. Escandell, Mafalda M. Dias, Iona McCall, Daniel Machado, Victor Cairns, Christine DeMaria, John J. Scarcelli   +13 more
wiley   +1 more source

Slimehead Size Through Time: Testing the Temperature-Size Relationship in Late Cretaceous Trachichthyidae. [PDF]

Ecol Evol
Griffiths CV, Witts JD, Brown JCS, Bernard EL, Twitchett RJ.   +4 more
europepmc   +1 more source

Innovative methodology for flexible monitoring of various bioprocesses by using pre‐existing Raman data coupled with automated transfer learning technique

Biotechnology Progress, EarlyView.
The application of the transfer learning algorithm successfully allowed the use of a model built on process A for real‐time monitoring of process B. This study shows the improvement obtained with this methodology compared to the direct application of the model.
Adèle Schini, Hadi El Radi, Johan Cailletaud, Célia Sanchez, Nathan Gay, Bruno Ebel, Emmanuel Guedon, Laurent Jourdainne   +7 more
wiley   +1 more source

Sex-specific resource strategies mediate home range sizes of an endangered carnivore across multiple scales. [PDF]

Sci Rep
Smith MM, Veals Dutt AM, Lombardi JV, Branney AB, Reeves AM, Scognamillo DG, Sergeyev M, Wardle ZM, Tewes ME, Petracca LS.   +9 more
europepmc   +1 more source

Annual Reports to the ESA Council ESA 110th Annual Meeting July, 2025

The Bulletin of the Ecological Society of America, EarlyView.
wiley   +1 more source