Results 71 to 80 of about 30,650 (267)

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

Advanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma, Yaqing Chen, Yiwen Gao, Xueting Hu, Qun Yang, Yucheng Liu, Peiyong Xin, Jijun Yan, Jinfang Chu, Lei Li, Zhixi Tian, Bo Ren   +11 more
wiley   +1 more source

PRODUCTIVITY OF SELAMBAU (FILTERING DEVICE) OPERATED IN THE WATERS OF SAPALA VILLAGE, SOUTH KALIMANTAN PROVINCE, INDONESIA [PDF]

Russian Journal of Agricultural and Socio-Economic Sciences
The objectives of this research are: 1) Describe the Selambau used in the waters of Sapala Village, Paminggir District, Hulu Sungai Utara Regency, South Kalimantan Province; 2) Analyze the composition and proportion and frequency of appearance of fish ...
Iriansyah, Riyandi A.
doaj  

Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation

Advanced Science, EarlyView.
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan, Ting‐Hui Lee, Tzu‐Ning Peng, Eva Yi‐Hsuan Wu, Yu‐Ting Chiu, Chih‐Chien Chiu, Hong Vinh Nguyen, Yuan‐Shao Pao, Ming‐Hong Chao, Richard Kuan‐Lin Lee, Han‐Chung Wu, Lily Hui‐Ching Wang   +11 more
wiley   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Analysis of productive and biological parameters of age-1+ carp crossbreed obtained by synthetic selection method in the Polissya zone of Ukraine

Ribogospodarsʹka Nauka Ukraïni
Purpose. To provide a comprehensive productive and biological characteristic and conduct a comparative analysis of the main productive parameters between purebred age-1+ Lyubin scaly carps and crossbreeds, which were obtained from crossing the offspring ...
H. Kurinenko, U. Kuts, М. Ostapchuk, S. Yurchak   +3 more
doaj   +1 more source

CLIMATE CHANGES AND CURRENT STATE OF BIOTA IN THE RUSSIAN WATERS OF THE FAR-EASTERN SEAS

Известия ТИНРО, 2019
Discussion about limiting influence of climate conditions on dynamics of the pacific salmon populations and generally on biological resources of the Far-Eastern Seas is continuing.
V. P. Shuntov, O. A. Ivanov
doaj   +1 more source

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

Advanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal, Ronald Garcia, Guangyi Chen, Chantal D. Bader, Peter Sullivan, Alexander Popoff, Daniel Krug, Maja Hunter, Sebastian Walesch, Emilia Oueis, Christine Frank, Haowen Zhao, Joachim J. Hug, Sebastian Keller, Pascal Hirsch, Azat Tagirdzhanov, Tatiana Malygina, Mary Victory E. Gutierrez, Alexey Gurevich, Judith Boldt, Boyke Bunk, Jörg Overmann, Ulrich Nübel, Andreas Keller, Olga V. Kalinina, Rolf Müller   +25 more
wiley   +1 more source

Size spectra assess social-ecological impacts on Amazonian fish assemblages

Ecological Indicators
Finding easily accessible indicators to assess the biodiversity conservation is crucial in regions where long-term monitoring data is deficient. This is particularly true for tropical freshwater ecosystems, which house most of the known fish biodiversity
Victoria J. Isaac, Leandro Castello, Nelson A. Gouveia, Jansen A.S. Zuanon, Fernanda A. Martins, Rivetla Edipo Araujo Cruz, Rodrigo O. Campos, Caroline C. Arantes, Gabriel C. Borba, Morgana Carvalho de Almeida, Claudia Pereira de Deus, Carolina R.C. Dória, Marilia Hauser, Carlos E. Freitas, Tommaso Giarrizzo, Alexandre P. Hercos, Giulia C. Lopes Carvalho, Elineide E. Marques, Raimundo Nonato G. Mendes-Júnior, Ualerson Iran Peixoto, Nelson Silva Pinto, Renato A.M. Silvano, Flavia K. Siqueira Souza, Ariana Cella-Ribeiro, Gislene Torrente-Vilara, Kedma C. Yamamoto, Filipe M. França   +26 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source