Results 91 to 100 of about 30,650 (267)

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

open access: yesAdvanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li   +9 more
wiley   +1 more source

Current state of ichthyofauna and use of aquatic bioresources in the Khrystoforivske Reservoir (Bokovenka River, Dnipro basin)

open access: yesRibogospodarsʹka Nauka Ukraïni
Purpose. To investigate the current state of the ichthyofauna in the Khrystoforivske Reservoir (nearshore and pelagic fish communities), the peculiarities of the distribution of fish communities, their abundance, as well as bioproduction capabilities ...
D. Kobyakov   +3 more
doaj   +1 more source

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

open access: yesAdvanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang   +7 more
wiley   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

open access: yesAdvanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen   +9 more
wiley   +1 more source

Streamlined V3.5+ Electrolyte Production by Leveraging Chemical and Catalytic Reductions

open access: yesAdvanced Energy Materials, EarlyView.
A tuned catalytic process for V3.5+ electrolyte production is shown to streamline the conventional chemical‐to‐catalytic sequence by extending catalysis into the rate‐determining reduction regime. This study shows that initiating catalysis in this regime shortens the overall production time by 67% based on rigorous thermodynamic and kinetic analysis of
Kyunghwa Seok   +2 more
wiley   +1 more source

A Compact Hollow Fiber Electrode Assembly Architecture for Continuous Electrochemical Marine Carbon Dioxide Removal

open access: yesAdvanced Energy Materials, EarlyView.
A coaxial, membrane‐integrated hollow fiber electrode assembly (HFEA) is developed for continuous marine carbon mineralization. By utilizing a sub‐millimeter inter‐electrode gap, the HFEA minimizes Ohmic losses, achieving 50% energy reduction and over 85% DIC removal.
Inhwan Park   +5 more
wiley   +1 more source

Temporary Programs, Lasting Questions: Ad Hoc Assistance in the U.S. Farm Safety Net

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Large ad hoc assistance programs have returned to U.S. farm policy since 2017, operating alongside a more developed safety net built around federally subsidized crop insurance, Title I commodity programs, and standing disaster assistance. This paper reviews the renewed use of ad hoc assistance, documents its recent scale using USDA data, and ...
Alejandro Plastina   +1 more
wiley   +1 more source

Environment drives forage fish productivity. [PDF]

open access: yesProc Natl Acad Sci U S A, 2015
Szuwalski CS, Hilborn R.
europepmc   +1 more source

Voluntary Collective Action to Address Growing Agricultural Challenges in Two Countries: Experimental Insights and Commonalities

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT We conducted two framed field economic experiments with citrus farmers in Florida, United States and soybean farmers in Argentina to investigate their willingness to coordinate pest and weed management efforts. Despite the contrast between these two agricultural contexts, we find striking behavioral commonalities.
Ariel Singerman, Sergio H. Lence
wiley   +1 more source

Results of growing age-1+ common carp (Cyprinus carpio Linnaeus, 1758) in ponds with the introduction of microalgae to their feed composition

open access: yesRibogospodarsʹka Nauka Ukraïni
Purpose. To investigate the productive performance of age-1+ common carp when partially replacing meat-and-bone meal with different amounts of a mixture of dry microalgae chlorella (Chlorella vulgaris) and spirulina (Spirulina platensis) as part of the ...
A. Tybinka   +3 more
doaj   +1 more source

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