Results 171 to 180 of about 2,621,603 (277)

Perfluorooctane sulfonate (PFOS) interferes with Cyp1a activity and dysregulates the aryl hydrocarbon receptor pathway in larval zebrafish (Danio rerio). [PDF]

Environ Pollut
Miller DH, Lachapelle A, Satbhai KM, Chien P, Borys KA, Timme-Laragy AR.   +5 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Genome-Wide Characterization of the Myostatin Gene (MSTN) Ligand-Receptor System and Its Expression Patterns Associated with Growth Variation in <i>Trachinotus ovatus</i>. [PDF]

Int J Mol Sci
Zhou JM, Guo HY, Zhu TF, Xian L, Liu BS, Zhang N, Zhu KC, Zhang DC.   +7 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Plant and Animal Protein Sources in Inflammatory Bowel Disease: Current Evidence and Clinical Implications. [PDF]

JGH Open
Mohamedrashed M, Chauhan A, Svolos V, Vasudevan A, Yao CK.   +4 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

The Vaccine Candidates Against Major Fish Pathogens (<i>Pseudomonas fluorescens</i> and <i>Aeromonas hydrophila</i>) from the Outer Membrane Proteins of <i>P. fluorescens</i> in Fish. [PDF]

Life (Basel)
Liu X, Sun W, Zhu L, Zhan Y, Yu Y, Wang K, Hu Q, Huang X, Lu J, Liu X.   +9 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Transcriptomic and Proteomic Insights into Mucosal Immune Responses of Asian Seabass (<i>Lates calcarifer</i>) After Sequential Mucosal Vaccination Against Bacterial Pathogens. [PDF]

Int J Mol Sci
Rodwihok C, Thompson KD, Meachasompop P, Kumwan B, Adisornprasert Y, Chaemlek P, Srisapoome P, Thangsunan P, Thangsunan P, Buncharoen W, Kingwascharapong P, Rodkhum C, Paankhao N, Uchuwittayakul A.   +13 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source