Results 151 to 160 of about 11,203,193 (300)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Policy for Australia : speech by the Hon. A. Fisher, leader of the federal Labor Party, at Gympie, 30th March, 1909.

, 1910
Cover title.; Added t.p.: The Fisher policy.; Electronic reproduction. Canberra, A.C.T.
Fisher, Andrew, 1862-1928.
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Letter to Snooky [Rosemary "Snooky" Fisher]

Letter written to Rosemary "Snooky" Snook on George Fisher's personalized "Mac" character stationery. Fisher wrote the letter while stationed in Greiz, Germany, in World War II.
Fisher, George, 1923-2003
core   +1 more source

FFAR2 activation induces IL-22-dependent intestinal immune responses to suppress CNS autoimmunity. [PDF]

EMBO Mol Med
Jevtić B, Lazarević M, Stegnjaić G, Stanisavljević S, Pilipović I, Nikolovski N, Milosavljević Z, Momčilović M, Koprivica I, Jonić N, Mićanović D, Radulović N, Marković M, Mirković K, Mišić D, Gašić U, Nikolić F, Veselinović N, Körner H, Grimm L, Lodygin D, Flügel A, Fraser G, Saksida T, Dimitrijević M, Stojanović I, Miljković Đ.   +26 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Is the fisher effect for real?: testing the long run fisher effect in selected european economies

, 2006
Στην εργασία χρησιμοποιούνται μεταπολεμικά μηνιαία στοιχεία για την Γαλλία , την Ιταλία και το Ηνωμένο Βασίλειο για να εξεταστεί η Υπόθεση Fisher για την σχέση ανάμεσα στον πληθωρισμό και τα βραχυχρόνια ονομαστικά επιτόκια (short-term nominal interest rates).
openaire   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source