Results 161 to 170 of about 2,123,873 (298)

Pirfenidone Reduces Intracochlear Fibrosis Caused by Cochlear Implantation in a Guinea Pig Model. [PDF]

Int J Mol Sci
Braack KJ, Short KL, Plester J, Miles T, Lim LY, Atlas MD, Kuthubutheen J, Mulders WHAM, Prêle CM.   +8 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Evaluating Trends in Bleeding Complications Associated with Metabolic Bariatric Surgery: A 14-Year Single-Center Experience. [PDF]

J Clin Med
Maxim M, Soroceanu PR, Pînzariu AC, Vlăsceanu VI, Ambrosie L, Platon LR, Onofriescu A, Balan G, Filip A, Grigore RG, Lupușoru RV, Trofin AG, Timofte DV.   +12 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Modulation of the stress-activated protein kinases Hog1/p38 and a TORC1-dependent kinase by curcumin is stress granule-dependent. [PDF]

J Biol Chem
Zheng L, Cherry ZK, Soltys G, Penner M, Samuell N, Welivita D, Thomas B, Fisher JS, Wang Y.   +8 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Human iPSC cardiomyocyte patch transplantation modifies extracellular matrix and fibroblast behavior after myocardial infarction. [PDF]

iScience
Torigata K, Matsuura R, Nagatomo F, Thiha M, Hikita T, Iseoka H, Takagi H, Koshimizu U, Sakakima H, Izumi S, Hatano A, Braun T, Sawa Y, Miyagawa S, Nakayama M.   +14 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Cytokines IL-6, IL-10, and CCL5 Secreted by Infiltrating B Cells Promote Cell Migration of Human Prostate Cancer Cell Lines. [PDF]

Oncol Res
Byrd CJ, Evans M, Kim W, Knight Q, Liou GY.   +4 more
europepmc   +1 more source

Is the fisher effect for real?: testing the long run fisher effect in selected european economies

, 2003
Στην εργασία χρησιμοποιούνται μεταπολεμικά μηνιαία στοιχεία για την Γαλλία , την Ιταλία και το Ηνωμένο Βασίλειο για να εξεταστεί η Υπόθεση Fisher για την σχέση ανάμεσα στον πληθωρισμό και τα βραχυχρόνια ονομαστικά επιτόκια (short-term nominal interest rates).
openaire   +1 more source