Results 41 to 50 of about 2,123,873 (298)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

“Fisher Effect” Theory and “Fisher Paradox” in China’s Economy

open access: yesOpen Journal of Social Sciences, 2015
“Fisher Effect” is the famous theoretical assumption about the interest rate and inflation rate. The paper first elaborates the basic principle of “Fisher Effect” theory, then finds the “Fisher Paradox” that may exist in China’s economy from the domestic and foreign scholars’ empirical study.
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The Relationship between the Exchange Rate, Interest Rate and Inflation: The Case of Turkey

open access: yesScientific Annals of Economics and Business, 2020
The purpose of the study is to measure the effects of changes in exchange rates and interest rates on inflation and to determine which of the exchange rates or interest rates has a greater impact on inflation rate following the July 15, 2016 coup attempt
Ercan Özen   +2 more
doaj  

Decomposition of Energy Intensity in the Iranian Manufacturing Industries [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2008
In this paper, we study the factors affecting changes in energy intensity in Iran. We use Fisher Ideal index in order to decompose the energy intensity into the structural changes and efficiency improvements in the Iranian manufacturing industries during
Alimorad Sharifi   +3 more
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Metrologically useful states of spin-1 Bose condensates with macroscopic magnetization

open access: yes, 2017
We study theoretically the usefulness of spin-1 Bose condensates with macroscopic magnetization in a homogeneous magnetic field for quantum metrology. We demonstrate Heisenberg scaling of the quantum Fisher information for states in thermal equilibrium ...
Kajtoch, Dariusz   +2 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Perceived Effects of Sand Dredging on Livelihood Diversification of Artisanal Fisher Folks in Lagos State, Nigeria

open access: yesAgricultura Tropica et Subtropica, 2017
The study examined perceived effects of sand dredging activities on livelihood diversification of artisanal fisher folks in Lagos State, Nigeria. Multi-stage sampling procedure was used to select respondents for the study.
Adesina Thomas Kehinde   +1 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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