Results 61 to 70 of about 2,123,873 (298)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Nonlinear Fault Separation for Redundancy Process Variables Based on FNN in MKFDA Subspace
Journal of Applied Mathematics, 2014 Nonlinear faults are difficultly separated for amounts of redundancy process variables in process industry. This paper introduces an improved kernel fisher distinguish analysis method (KFDA).
Ying-ying Su +5 more
doaj +1 more source
On the Sum of Fisher-Snedecor F Variates and its Application to Maximal-Ratio Combining
, 2018 Capitalizing on the recently proposed Fisher-Snedecor F composite fading model, in this letter, we investigate the sum of independent but not identically distributed (i.n.i.d.) Fisher-Snedecor F variates.
Badarneh, Osamah. S. +4 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
An econometric analysis of the effects of macroeconomic variables on interest rates in Brazil
Economia Aplicada, 1998 This paper examines the importance of liquidity, credit, and Fisher effects on the interest rate in Brazil during the period 1975-1991, for five different segments of the financial market.
Fernando Blumenschein
doaj
, 2014 In a two-mode Bose-Josephson junction formed by a binary mixture of ultracold atoms, macroscopic superpositions of phase states are produced during the time evolution after a sudden quench to zero of the coupling amplitude. Using quantum trajectories and
Ferrini, Giulia +3 more
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Cogent Economics & FinanceThe failure of the Federal Reserve Bank to control inflation within its target range has raised concerns about potential misunderstandings in US monetary policy dynamics.
Andrew Phiri
doaj +1 more source
Panel cointegration analysis of the Fisher effect: Evidence from the US, the UK, and Japan [PDF]
This paper analyzes the Fisher effect using a panel of monthly data from January 1990 to December 2010 for three major countries: the United States, the United Kingdom, and Japan.
Shigeyuki Hamori, Yuki Toyoshima
core