Results 81 to 90 of about 11,203,193 (300)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Structural breaks, cointegration and the Fisher effect [PDF]
There is scant empirical support in the literature for the Fisher effect in the long run, though it is often assumed in theoretical models. We argue that a break in the cointegrating relation introduces a spurious unit root that leads to a rejection of ...
Haug, Alfred A. +2 more
core
Envelope with Artwork for a Letter from Fisher to His Wife, Rosemary
, 1950 Envelope with art work for a letter from Fisher to his wife. In addition to the recipient's name and address, there is an image of a barefoot hillbilly character delivering letters and gifts in a one-wheeled wooden cart to the addressee, Mrs.
Fisher, George, 1923-2003
core +1 more source
Does the Fisher effect hold in Rwanda? [PDF]
Qual Quant, 2023 Ruzima M +3 more
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Is the Fisher Effect for Real? A Reexamination of the Relationship Between Inflation and Interest Rates [PDF]
The basic puzzle about the so-called Fisher effect, in which movements in short-term interest rates primarily reflect fluctuations in expected inflation, is why a strong Fisher effect occurs only for certain periods but not for others.
Frederic S. Mishkin
core
Too Good to be False: Nonsignificant Results Revisited
Collabra: Psychology, 2017 Due to its probabilistic nature, Null Hypothesis Significance Testing (NHST) is subject to decision errors. The concern for false positives has overshadowed the concern for false negatives in the recent debates in psychology.
Chris H. J. Hartgerink +2 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
George Fisher at the Drawing Board Searching for Cartoon Ideas
, 1995 Cartoon by Fisher of a cartoonist holding his head in his hands and surrounded by cartoon images of well-known political figures. Woman's text bubble on recto: "No idea for a cartoon?
Fisher, George, 1923-2003
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source