Results 111 to 120 of about 4,485,260 (310)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Diagnostic Accuracy of Microsoft’s Copilot Artificial Intelligence in Chronic Wound Assessment: A Comparative Study

open access: yesPlastic and Reconstructive Surgery, Global Open
Background:. Chronic wounds affect approximately 2.5% of the US population and can cause severe complications if not identified and treated promptly. Artificial intelligence tools such as Microsoft’s Copilot have the potential to expedite diagnosis, but ...
Kirollos Tadrousse, BS   +4 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Testing the Neo-Fisher Hypothesis in Norway

open access: yes, 2023
The existence of low nominal interest rates and inflation below target after the global financial crisis in 2008 has made some economists question the causality of the Fisher equation. As the traditional theory states that the causality in the long-run Fisher equation runs from inflation rates to interest rates, the Neo-Fisher hypothesis reverses this ...
openaire   +1 more source

The Roy B. Fisher, D.O. Collection

open access: yes, 1998
Finding aid for the Roy B. Fisher, D.O. CollectionRoy Benjamin Fisher, D.O. (1910-1998), was a prominent physician in Fort Worth, Texas and one of founders of the Fort Worth Osteopathic Hospital (later the Osteopathic Medical Center of Texas).
Fisher, Roy B.
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Attuali sviluppi nello studio dell’associazione tra variabili di tipo qualitativo.

open access: yesRatio Mathematica, 1996
The most common procedure for analyzing contingency table data is by using chi-square statistic. The early development of chi-square analysis of contingency table is credited to Pearson (1904) and Fisher (1929), successively expanded by Yates, Mantel ...
C Antonelli, E Ballone
doaj  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

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