Results 41 to 50 of about 923,861 (295)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Stochastic Complexity of Rayleigh and Rician Data with Normalized Maximum Likelihood
StatsThe Rician distribution, which arises in radar, communications, and magnetic resonance imaging, is characterized by a noncentrality parameter and a scale parameter.
Aaron Lanterman
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Journal of Hymenoptera Research, 2015 A new genus and species of Ichneutinae s. l., Colemanus keeleyorum Fisher, is described from the Eocene Green River Formation in Colorado, USA. Colemanus was placed on a phylogenetic hypothesis using morphological data.
J. Fisher, Erika Tucker, Michael Sharkey
doaj +1 more source
Does Amount of Information Support Aesthetic Values?
Frontiers in Neuroscience, 2022 Obtaining information from the world is important for survival. The brain, therefore, has special mechanisms to extract as much information as possible from sensory stimuli.
Norberto M. Grzywacz +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Microarrays, Empirical Bayes and the Two-Groups Model [PDF]
, 2008 The classic frequentist theory of hypothesis testing developed by Neyman, Pearson and Fisher has a claim to being the twentieth century's most influential piece of applied mathematics.
Efron, Bradley
core +5 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Consistency and Asymptotic Normality of the Maximum Likelihood Estimator in
IEEE Access, 2022 The Gamma distribution based generalized linear model ( $Ga$ GLM) is a kind of statistical model feasible for the positive value of a non-stationary stochastic system, in which the location and the scale are regressed by the corresponding explanatory ...
Benchao Wang, Pan Qin, Hong Gu
doaj +1 more source
The spacetime structure of MOND with Tully-Fisher relation and Lorentz invariance violation
, 2012 It is believed that the modification of Newtonian dynamics (MOND) is possible alternate for dark matter hypothesis. Although Bekenstein's TeVeS supplies a relativistic version of MOND, one may still wish a more concise covariant formulism of MOND.
Angus G W +16 more
core +1 more source