Results 131 to 140 of about 739,441 (301)
A Pessimistic Approximation for the Fisher Information Measure [PDF]
, 2016 Manuel Stein, Josef A. Nossek
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Fisher's information measures and truncated normal distributions (II)
Journal of Numerical Analysis and Approximation Theory, 2003 The aim of this paper is to give some properties for the Fisher information measure when a random variable \(X\) follows a truncated probability distribution.
Ion Mihoc, Cristina Ioana Fătu
doaj
Entanglement and Fisher Information for Atoms-Field System in the Presence of Negative Binomial States. [PDF]
Entropy (Basel), 2022 Berrada K +3 more
europepmc +1 more source
Sensitivity Analysis for Binary Sampling Systems via Quantitative Fisher Information Lower Bounds [PDF]
, 2015 Manuel Stein
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Square Root Convexity of Fisher Information along Heat Flow in Dimension Two. [PDF]
Entropy (Basel), 2023 Liu J, Gao X.
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source