Results 131 to 140 of about 795,540 (289)
Estimation of signal information content for classification
, 2009 Information measures have long been studied in the context of hypothesis testing leading to variety of bounds on performance based on the information content of a signal or the divergence between distributions.
Michael Siracusa +5 more
core +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Robert Fisher is standing and holding a cigar. Autograph on recto: "Robert Fisher."Robert Fisher was a journalist for the Arkansas Democrat responsible for helping pass the Freedom of Information Act in 1967 and was called on by Bill Clinton, Arkansas ...
Fisher, George, 1923-2003
core
Fisher Information Matrix And Hyperbolic Geometry
, 2015 The Fisher information matrix induces a metric on parametric spaces of families of probability density functions. We analyse here the family of normal distributions showing how hyperbolic geometry arises naturally from the Fisher information metric ...
Santos S.A. +2 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Fisher information matrix of binary time series
, 2018 A common approach to analyzing categorical correlated time series data is to fit a generalized linear model (GLM) with past data as covariate inputs. There remain challenges to conducting inference for time series with short length.
Gillen, Daniel, Ombao, Hernando, Gao, Xu
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Fisher Information for a System Composed of a Combination of Similar Potential Models
Quantum ReportsThe solutions to the radial Schrödinger equation for a pseudoharmonic potential and Kratzer potential have been studied separately in the past. Despite different reports on the Kratzer potential, the fundamental theoretical quantities such as Fisher ...
Clement Atachegbe Onate +7 more
doaj +1 more source
Fisher Information as General Metrics of Quantum Synchronization. [PDF]
Entropy (Basel), 2023 Shen Y, Soh HY, Kwek LC, Fan W.
europepmc +1 more source