Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Predictions of the accuracy of genomic prediction: connecting R2, selection index theory, and Fisher information. [PDF]
Genet Sel Evol, 2022 Bijma P, Dekkers JCM.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Generalized Kramer–Rao inequality for the moments of distribution of estimation error
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 In this paper it's obtained a generalized system of statistical inequalities under additional conditions of regularity of the statistical experiment, which is a generalization of the Cramer–Rao inequality.
A. V. Ausiannikau, V. M. Kozel
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Cumulative Residual q-Fisher Information and Jensen-Cumulative Residual χ2 Divergence Measures. [PDF]
Entropy (Basel), 2022 Kharazmi O, Balakrishnan N, Jamali H.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Quantum Fisher information of two atoms with dipole-dipole interaction under the environment of phase noise lasers. [PDF]
Sci Rep, 2021 Chen Y, Long ZW, He Z, Ji ST.
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Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Multiscale feature fusion for few-shot medical image learning with fisher information-driven layer selection. [PDF]
Vis Comput Ind Biomed ArtZhang K, Peng Y, Pang B, Chen X.
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