Results 51 to 60 of about 235,085 (295)
Fisher Information in Helmholtz–Boltzmann Thermodynamics of Mechanical Systems
FoundationsIn this paper, we review Helmholtz–Boltzmann thermodynamics for mechanical systems depending on parameters, and we compute the Fisher information matrix for the associated probability density.
Marco Favretti
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On Fisher's information matrix of an ARMAX process and Sylvester's resultant matrices [PDF]
Linear Algebra and its Applications, 1996 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Klein, A.A.B., Spreij, P.J.C.
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Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
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Entropy, 2014 We investigate the asymptotic construction of constant-risk Bayesian predictive densities under the Kullback–Leibler risk when the distributions of data and target variables are different and have a common unknown parameter. It is known that the Kullback–
Keisuke Yano, Fumiyasu Komaki
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Observability and fisher information matrix in nonlinear regression [PDF]
IEEE Transactions on Aerospace and Electronic Systems, 2007 This paper is devoted to the link between the Fisher information matrix (FIM) invertibility and the observability of a parameter to be estimated in a nonlinear regression problem.
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
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Uncertainty of Volatility Estimates from Heston Greeks
Frontiers in Applied Mathematics and Statistics, 2018 Volatility is a widely recognized measure of market risk. As volatility is not observed it has to be estimated from market prices, i.e., as the implied volatility from option prices. The volatility index VIX making volatility a tradeable asset in its own
Oliver Pfante, Nils Bertschinger
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
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A stronger version of matrix convexity as applied to functions of Hermitian matrices
Journal of Inequalities and Applications, 1999 A stronger version of matrix convexity, called hyperconvexity is introduced. It is shown that the function is hyperconvex on the set of Hermitian matrices and is hyperconvex on the set of positive definite Hermitian matrices. The new concept makes it
Kagan Abram, Smith Paul J
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