Results 71 to 80 of about 62,953 (258)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
A Fisher–Rao Metric for Curves Using the Information in Edges [PDF]
Journal of Mathematical Imaging and Vision, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How Interactions Affect Many-Body States Distinguishability: A Geometric Viewpoint
DynamicsWe investigate the information-geometric structure of a self-consistent second-virial approximation with the van der Waals form of the second virial coefficient, using the Fisher information as a generating potential.
Flavia Pennini, Angelo Plastino
doaj +1 more source
On Voronoi Diagrams on the Information-Geometric Cauchy Manifolds
Entropy, 2020 We study the Voronoi diagrams of a finite set of Cauchy distributions and their dual complexes from the viewpoint of information geometry by considering the Fisher-Rao distance, the Kullback-Leibler divergence, the chi square divergence, and a flat ...
Frank Nielsen
doaj +1 more source
Fisher-Rao Metric, Geometry, and Complexity of Neural Networks
CoRR, 2017 We study the relationship between geometry and capacity measures for deep neural networks from an invariance viewpoint. We introduce a new notion of capacity --- the Fisher-Rao norm --- that possesses desirable invariance properties and is motivated by Information Geometry. We discover an analytical characterization of the new capacity measure, through
Liang, T +3 more
openaire +4 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Geometry of State-Update Processes and Wave Function Collapse
Quantum ReportsWe develop an information-geometric framework for describing quantum state-update processes associated with measurement and statistical distinguishability.
Angelo Plastino
doaj +1 more source
Results on common fixed points
International Journal of Mathematics and Mathematical Sciences, 2001 We establish common fixed point theorems related with families of self mappings on metric spaces. Our results extend, improve, and unify the results due to Fisher (1977, 1978, 1979, 1981, 1984), Jungck (1988), and Ohta and Nikaido (1994).
Zeqing Liu, Jeong Sheok Ume
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source