Results 61 to 70 of about 62,953 (258)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Lie Group Cohomology and (Multi)Symplectic Integrators: New Geometric Tools for Lie Group Machine Learning Based on Souriau Geometric Statistical Mechanics

open access: yesEntropy, 2020
In this paper, we describe and exploit a geometric framework for Gibbs probability densities and the associated concepts in statistical mechanics, which unifies several earlier works on the subject, including Souriau’s symplectic model of statistical ...
Frédéric Barbaresco   +1 more
doaj   +1 more source

Riemannian geometry of optimal driving and thermodynamic length and its application to chemical reaction networks

open access: yesPhysical Review Research, 2022
It is known that the trajectory of an endoreversibly driven system with minimal dissipation is a geodesic on the equilibrium state space. Thereby, the state space is equipped with the Riemannian metric given by the Hessian of the free energy function ...
Dimitri Loutchko   +2 more
doaj   +1 more source

On the Incompleteness of Birkhoff’s Theorem: A New Approach to the Central Symmetric Gravitational Field in Vacuum Space

open access: yesReports in Advances of Physical Sciences, 2023
Birkhoff’s theorem (1923) states that in the framework of General Relativity the only solution to the central symmetric gravitational field in vacuum is the Schwarzschild metric.
Michel Canac
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Common fixed point theorems for a weak distance in complete metric spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
Using the concept of a w-distance, we obtain common fixed point theorems on complete metric spaces. Our results generalize the corresponding theorems of Jungck, Fisher, Dien, and Liu.
Jeong Sheok Ume, Sucheol Yi
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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