Results 121 to 130 of about 1,045,272 (385)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

eDNA Sampling Systems for Salmon Ecosystem Monitoring

Environmental DNA
Environmental DNA (eDNA) is transforming the way aquatic ecosystems are monitored and managed by scientists, resource managers, ENGOs, First Nations communities, and citizen scientists alike.
Christoph M. Deeg, Robert G. Saunders, Christopher Tam, Karia Kaukinen, Shaorong Li, Arthur L. Bass, Uu‐a‐thluk Fisheries, Kristina M. Miller   +7 more
doaj   +1 more source

Sustaining Aquatic Ecosystems in Boreal Regions

Ecology and Society, 1998
Few boreal waters are managed in a sustainable manner, because cumulative effects of a variety of human activities are not considered. Fisheries and water quality have declined in most large water bodies of the southern boreal zone.
David Schindler
doaj   +1 more source

Re-emphasizing the importance of Lake Chad fisheries in Nigerian economy: Borno State experience [PDF]

, 2003
Nigeria with an estimated population of about 120 million people requires about 2.3 million metric tonnes of fish and fisheries product for good health at the recommended 19 kg/caput/year by FAO.
Odogbo, D.
core  

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

A fisher's perspective: Using half a century of local fisher knowledge to identify socio‐economic, ecological and legislative trends influencing angelshark (Squatina squatina) records in Wales

People and Nature
The evolution of marine fisheries has broadly influenced the ecology, distribution and abundance of coastal elasmobranchs. However, quantifying these interactions remains a challenge due to the scarcity of historical records.
Francesca C. Mason, Jake Davies, Surshti Patel, Ben Wray, Charlie Bartlett, Michael Davies, Rowland Sharp, Carl Worrall, Jim Evans, John O'Connor, Sarah Davies, Alice Chamberlain, Charlotte Pike, Kathryn E. Whittey, Claire Collins, Matthew Gollock, Joanna Barker, David J. Curnick   +17 more
doaj   +1 more source

Fisheries and Fishery Management in a Variable Climate

, 2017
Fisheries around the world are in collapse despite decades of research and attempts to manage them. While conventional bioeconomic models of fishery depletion are well-understood, reversing these trends has proven to be a stubborn problem, even in the presence of science-based management regimes.
openaire   +3 more sources

Eden Fisheries Advisory Committee 29th April, 1975 [PDF]

, 1975
This is the report from the Eden Fisheries Advisory Committee meeting, which was held on the 29th April, 1975. It covers information on fishery byelaws, and a report by unit fisheries officer on fisheries activities.

core  

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Connecting the Dots: Linking Sustainable Wild Capture Fisheries Initiatives and Impact Investors [PDF]

, 2016
Wilderness Markets undertook a series of fishery value chain assessments to better understand the opportunities and constraints for private impact capital to flow into wild capture fisheries markets.

core