Results 181 to 190 of about 156,022 (264)

Effects of <i>Lumbricus</i> sp. Extract Supplementation Methods and Levels in Fermented Feed on Digestibility, Growth, Gut Emptying, Blood Glucose and Phagocytic Parameters of Milkfish, <i>Chanos chanos</i> (Forsskal, 1775). [PDF]

Trop Life Sci Res
Aslamyah S, Yunus YE, Kasan NA, Mohammed AA.   +3 more
europepmc   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Genetic Diversity and Structure Analysis of Wild Oysters (<i>Crassostrea virginica</i>) Within and Between River Systems Reveals Spatial Genetic Structure and Salinity-Adaptive Variation Across the Canadian Maritimes. [PDF]

Evol Appl
Hall S, Méthé D, Steeves R, LaFlamme M, Dinn C, Sonier R, Clements JC.   +6 more
europepmc   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Long-Read Metagenomics Reveals Temporal DNA Virome Dynamics and Recovers Sequences of a Major Viral Pathogen at a Sea-Cage Fish Farm. [PDF]

Microorganisms
Kim A, Moon SB, Kim JS, Kim MS, Lee Y, Kang G, Kim KH, Roh H.   +7 more
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Prioritizing Shark, Ray, and Chimaera Conservation in Rapidly Changing Polar Waters. [PDF]

Glob Chang Biol
Bettcher VB, Batlle-Morera A, Kyne PM, Charles R, García-Rodríguez E, Rohner CA, Armstrong AO, O'Leary Amsler M, Chernova NV, Devine BM, Dolgov AV, Donovan MM, Faure J, Finucci B, Fisher JAD, Forbes RAS, Hedges KJ, Hollyman PR, Hussey NE, Jac R, Kulka DW, Orlov AM, Péron C, Schaber M, Ste-Marie E, Weigmann S, Jabado RW.   +26 more
europepmc   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Stable In Vitro Cultivation of the Myxozoan <i>Enteromyxum leei</i> for over 12 Months: Integration of a Physical Aggregation Technique for Long-Term Antiparasitic Interventions. [PDF]

Pathogens
Jeon EJ, Seo HG, Kim NY, Kim A, Kim MS, Do JW, Han HJ, Kang HS, Woo SJ.   +8 more
europepmc   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source