Results 71 to 80 of about 156,022 (264)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Resource degradation, marginalization, and poverty in small-scale fisheries: threats to social-ecological resilience in India and Brazil

open access: yesEcology and Society, 2014
In this study we examine poverty in local fisheries using a social-ecological resilience lens. In assessing why "fishery may rhyme with poverty", Christophe Béné suggests a typology of impoverishment processes, which includes economic exclusion, social ...
Prateep K. Nayak   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

What You Know is Who You Know? Communication Patterns Among Resource Users as a Prerequisite for Co-management

open access: yesEcology and Society, 2006
The social networks is one factor determining the flow of information within communities and as such may be important in determining successful implementation of community based management. We mapped the social network used for communication of knowledge
Beatrice Crona, Örjan Bodin
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

eDNA Sampling Systems for Salmon Ecosystem Monitoring

open access: yesEnvironmental DNA
Environmental DNA (eDNA) is transforming the way aquatic ecosystems are monitored and managed by scientists, resource managers, ENGOs, First Nations communities, and citizen scientists alike.
Christoph M. Deeg   +7 more
doaj   +1 more source

Sustaining Aquatic Ecosystems in Boreal Regions

open access: yesEcology and Society, 1998
Few boreal waters are managed in a sustainable manner, because cumulative effects of a variety of human activities are not considered. Fisheries and water quality have declined in most large water bodies of the southern boreal zone.
David Schindler
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

A fisher's perspective: Using half a century of local fisher knowledge to identify socio‐economic, ecological and legislative trends influencing angelshark (Squatina squatina) records in Wales

open access: yesPeople and Nature
The evolution of marine fisheries has broadly influenced the ecology, distribution and abundance of coastal elasmobranchs. However, quantifying these interactions remains a challenge due to the scarcity of historical records.
Francesca C. Mason   +17 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

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