Results 81 to 90 of about 886,805 (321)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
South Lancashire Fisheries Advisory Committee 14th January, 1976. [PDF]
, 1976 This is the report from the South Lancashire Fisheries Advisory Committee meeting, which was held on the 14th January 1976. The report contains information on land drainage representation on local committees, fisheries activities report, pollution on ...
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Ecology and Society, 2014 We report on outcomes and lessons learned from a 15-month initiative in Cambodia's Tonle Sap Lake. Employing the appreciation-influence-control (AIC) model of participatory stakeholder engagement, the initiative built shared understanding of the sources
Blake D. Ratner, Kosal Mam, Guy Halpern
doaj +1 more source
The Threatened Status of Steller Sea Lions, Eumetopias jubatus, under the Endangered Species Act: Effects on Alaska Groundfish Fisheries Management [PDF]
, 1995 In April 1990, the Steller sea lion, Eumetopias jubatus, was listed as threatened under the U.S. Endangered Species Act by emergency action. Competitive interactions with the billion-dollar Alaska commercial groundfish fisheries have been suggested as ...
Berg , Ronald J. +2 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Acta Agriculturae Slovenica, 2011 To compare the sensorial quality of wild and farmed brown trout 34 consumer were asked to decide which of the two samples presented to them in double blind test was preferred regarding appearance, aroma, juiciness, mouth feeling and general impression if
Jurij POHAR
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Fisheries and Marine Resources of Hawaii and the U.S.-associated Pacific Islands: An Introduction [PDF]
, 1993 The fisheries of Hawaii and other U.S.-associated islands in the Pacific Ocean are characterized by high diversity, both in the species exploited and the human cultures that exploit them.
Boehlert , George W.
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source