Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim+9 more
wiley +1 more source
Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang+9 more
wiley +1 more source
Multispecies fisheries management of the Sultanate of Oman using bioeconomic model. [PDF]
Dutta S+3 more
europepmc +1 more source
Temporal and spatial comparison of food web structure in marine pastures in the Pearl River Estuary: Implications for sustainable fisheries management. [PDF]
Xu P, Zhou W, Xie M, Ding D, Suo A.
europepmc +1 more source
Impacts of demographic variation in spawning characteristics on reference points for fishery management [PDF]
S. A. Murawski+2 more
openalex +1 more source
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li+9 more
wiley +1 more source
Movement traits important to conservation and fisheries management: an example with red snapper. [PDF]
Lowerre-Barbieri SK+7 more
europepmc +1 more source
Fisheries management as a Stackelberg Evolutionary Game: Finding an evolutionarily enlightened strategy. [PDF]
Salvioli M+3 more
europepmc +1 more source
Distributional issues in the operation of rights-based fisheries management systems [PDF]
Olivier Guyader, Olivier Thébaud
openalex +1 more source