Results 71 to 80 of about 7,500,788 (286)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
MODEL PENGELOLAAN PERIKANAN BERBASIS HUKUM ADAT LAOT DI LHOK RIGAIH KABUPATEN ACEH JAYA
Masalah-Masalah Hukum, 2011 The concept of fisheries management in Indonesia, local wisdom to know the content community, as the Regulation No. 4512009 and Regulation no. 1112006. This study wanted to address how the model-based fisheries management /aot customary law in Aceh. This
Sulaiman Sulaiman
doaj +1 more source
FEBS Open Bio, EarlyView.Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli +4 more
wiley +1 more source
State of global fisheries – management policies
Contemporary Economy, 2013 Global fisheries landings have stagnated and are associated with many negative environmental impacts, affecting the economy and food security in many countries around the world.
Alicja Dabrowska, Lara D. Mateos
doaj
Methods in Ecology and EvolutionMost fisheries on commercially fished species are managed on a stock‐by‐stock basis through catch limits. When set in isolation, catch limits ignore mixed‐fisheries interactions that result from catches by fishing fleets comprising multiple stocks ...
Matthew C. Pace +3 more
doaj +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
FEBS Open Bio, EarlyView.This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma +10 more
wiley +1 more source
Social-ecological system network connectivity model on potential areas of other effective area-based conservation measures for fisheries in Kolono Bay [PDF]
BIO Web of ConferencesThis study aims to map the components of the social-ecological system (SES) in Kolono Bay based on the criteria of Other Effective Area-based Conservation Measures (OECM) Fisheries and identify key connectivity in its management. The approach used is SES
Auliyah Nurul +4 more
doaj +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
FEBS Open Bio, EarlyView.A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Frontiers in Marine Science, 2020 Non-compliance with regulations is a complex problem in recreational fisheries management, having the potential to evoke uncertainty for conservation and socio-ecological outcomes and to undermine management efforts.
Mary Mackay +9 more
doaj +1 more source
Assessing progress in data reporting by tuna Regional Fisheries Management Organizations [PDF]
, 2022 Kristina N. Heidrich +5 more
openalex +1 more source