Results 51 to 60 of about 44,186 (256)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

MixME: An R package to simulation‐test fisheries management robustness to mixed‐fisheries interactions

Methods in Ecology and Evolution
Most fisheries on commercially fished species are managed on a stock‐by‐stock basis through catch limits. When set in isolation, catch limits ignore mixed‐fisheries interactions that result from catches by fishing fleets comprising multiple stocks ...
Matthew C. Pace, José A. A. De Oliveira, Simon H. Fischer, Paul J. Dolder   +3 more
doaj   +1 more source

Snapper and grouper fisheries management in Aisandami using the EAFM approach [PDF]

BIO Web of Conferences
The coastal waters of Aisandami are rich in diverse coral fish resources, including snappers and groupers. A study is needed to evaluate how fisheries are managed in water.
Sala Ridwan, Kolibongso Duaitd, Kaber Yuanike, Wattimury Dougklas   +3 more
doaj   +1 more source

A comparison of sustainability objectives: how well does the Canadian Fisheries Research Network framework compare with fisheries, forestry, and aquaculture certification schemes?

Ecology and Society, 2020
It is increasingly recognized that fisheries management should take a more holistic approach toward full spectrum sustainability that includes ecological, social, and economic considerations.
Claire Mussells, Robert L. Stephenson
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

MODEL PENGELOLAAN PERIKANAN BERBASIS HUKUM ADAT LAOT DI LHOK RIGAIH KABUPATEN ACEH JAYA

Masalah-Masalah Hukum, 2011
The concept of fisheries management in Indonesia, local wisdom to know the content community, as the Regulation No. 4512009 and Regulation no. 1112006. This study wanted to address how the model-based fisheries management /aot customary law in Aceh. This
Sulaiman Sulaiman
doaj   +1 more source

Small-pelagic Small-pelagic fisheries management strategic using ecosystem approach at Belu Regency, East Nusa Tenggara

Journal of Natural Resources and Environmental Management, 2020
Study on small-pelagic fisheries in the border regions between Indonesia - Timor Leste has taken place in Belu District, East Nusa Tenggara. It was aimed to assess the status of small pelagic management and formulate the strategic and tactical steps for ...
Beatrix Maureen Rehatta, Mohammad Mukhlis Kamal, Mennofatria Boer, Achmad Fahrudin, Zairion   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

State of global fisheries – management policies

Contemporary Economy, 2013
Global fisheries landings have stagnated and are associated with many negative environmental impacts, affecting the economy and food security in many countries around the world.
Alicja Dabrowska, Lara D. Mateos
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source