Results 41 to 50 of about 8,891,761 (262)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Elasmobranch bycatch in US West Coast groundfish fisheries

Endangered Species Research, 2021
Effective management of multispecies fisheries in large marine ecosystems is challenging. To deal with these challenges, fisheries managers are moving toward ecosystem-based fishery management (EBFM).
JE Jannot, R Bjorkland, KA Somers, T Mitchell, VJ Tuttle, J McVeigh   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Review of Thai Laws in Relation to Trawl Fisheries, Bycatch Management Project “Strategies for Trawl Fisheries Bycatch Management” [PDF]

, 2014
Thailand: “A review of Thai Laws in Relation to Trawl Fisheries, Bycatch Management,” this study is a part of the project “Strategies for Trawl Fisheries Bycatch Management” (REBYC-II CTI; GCP/RAS/269/GFF).
Nettasna, Chintana
core  

Science and Fisheries Management [PDF]

, 1977
The W.J.N. Menzies Memorial Lecture delivered at the Annual Course of the Institute of Fisheries Management at the University of East Anglia, Norwich, on 16 September ...
Went, A E J
core   +1 more source

Snapper and grouper fisheries management in Aisandami using the EAFM approach [PDF]

BIO Web of Conferences
The coastal waters of Aisandami are rich in diverse coral fish resources, including snappers and groupers. A study is needed to evaluate how fisheries are managed in water.
Sala Ridwan, Kolibongso Duaitd, Kaber Yuanike, Wattimury Dougklas   +3 more
doaj   +1 more source

Fisheries Surveys Are Essential Ocean Observing Programs in a Time of Global Change: A Synthesis of Oceanographic and Ecological Data From U.S. West Coast Fisheries Surveys

Frontiers in Marine Science, 2022
As climate change and other anthropogenic impacts on marine ecosystems accelerate in the 21st century, there is an increasing need for sustained ocean time series.
Natalya D. Gallo, Noelle M. Bowlin, Andrew R. Thompson, Erin V. Satterthwaite, Briana Brady, Brice X. Semmens   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

MODEL PENGELOLAAN PERIKANAN BERBASIS HUKUM ADAT LAOT DI LHOK RIGAIH KABUPATEN ACEH JAYA

Masalah-Masalah Hukum, 2011
The concept of fisheries management in Indonesia, local wisdom to know the content community, as the Regulation No. 4512009 and Regulation no. 1112006. This study wanted to address how the model-based fisheries management /aot customary law in Aceh. This
Sulaiman Sulaiman
doaj   +1 more source

A comparison of sustainability objectives: how well does the Canadian Fisheries Research Network framework compare with fisheries, forestry, and aquaculture certification schemes?

Ecology and Society, 2020
It is increasingly recognized that fisheries management should take a more holistic approach toward full spectrum sustainability that includes ecological, social, and economic considerations.
Claire Mussells, Robert L. Stephenson
doaj   +1 more source